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Acute Effects of High-Intensity Interval Training on Diabetes Mellitus: A Systematic Review

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Publisher MDPI
Date 2022 Jun 24
PMID 35742298
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Abstract

This study evaluated the scientific evidence on the acute effects of high-intensity interval training (HIIT) on biochemical, cardiovascular, and metabolic parameters in patients with diabetes mellitus. The research took place using two databases (PubMed and Google Scholar) with eligible studies conducted between 2010 and 2020, using the following keywords: (1) high-intensity training/exercise; (2) interval training/exercise; (3) HIIT/exercise; AND "diabetes". Data extraction was then performed on the eligible studies through content analysis using the categories: author and year of publication; sample characteristics; methods and data collected; intervention protocol; and results found. Methodological quality was assessed using the PEDro scale. Fourteen studies were included, evaluating 168 people with diabetes (122/46 type 2/1) and 42 normoglycemic individuals, which evaluated markers such as capillary and fasting blood glucose, 24-h blood glucose profile, postprandial blood glucose, incidence, and prevalence of hyperglycemia, vascular function and pressure response and control of inflammatory markers. Physical exercise was found to have several acute beneficial effects on the health of the diabetic population, such as reduced capillary and postprandial blood glucose, blood glucose profile, and blood pressure. Moreover, HIIT seems to be a safe and effective alternative in glycemic control and associated factors, superior to continuous moderate-intensity training.

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References
1.
Kirwan J, Sacks J, Nieuwoudt S . The essential role of exercise in the management of type 2 diabetes. Cleve Clin J Med. 2017; 84(7 Suppl 1):S15-S21. PMC: 5846677. DOI: 10.3949/ccjm.84.s1.03. View

2.
Karstoft K, Christensen C, Pedersen B, Solomon T . The acute effects of interval- Vs continuous-walking exercise on glycemic control in subjects with type 2 diabetes: a crossover, controlled study. J Clin Endocrinol Metab. 2014; 99(9):3334-42. DOI: 10.1210/jc.2014-1837. View

3.
Karstoft K, Wallis G, Pedersen B, Solomon T . The effects of interval- vs. continuous exercise on excess post-exercise oxygen consumption and substrate oxidation rates in subjects with type 2 diabetes. Metabolism. 2016; 65(9):1316-25. DOI: 10.1016/j.metabol.2016.05.017. View

4.
Viana A, Fernandes B, Alvarez C, Guimaraes G, Ciolac E . Prescribing high-intensity interval exercise by RPE in individuals with type 2 diabetes: metabolic and hemodynamic responses. Appl Physiol Nutr Metab. 2018; 44(4):348-356. DOI: 10.1139/apnm-2018-0371. View

5.
Kelly B, Xenophontos S, King J, Nimmo M . An evaluation of low volume high-intensity intermittent training (HIIT) for health risk reduction in overweight and obese men. BMC Obes. 2017; 4:17. PMC: 5395873. DOI: 10.1186/s40608-017-0151-7. View