Advancements in Testing Strategies for COVID-19

Overview

Journal Biosensors (Basel)

Specialty Biotechnology

Date 2022 Jun 23

PMID 35735558

Authors

Rabia Asghar

Madiha Rasheed

Jalees Ul Hassan

Mohsin Rafique

Mashooq Khan

Yulin Deng

Affiliations

Soon will be listed here.

Abstract

The SARS-CoV-2 coronavirus, also known as the disease-causing agent for COVID-19, is a virulent pathogen that may infect people and certain animals. The global spread of COVID-19 and its emerging variation necessitates the development of rapid, reliable, simple, and low-cost diagnostic tools. Many methodologies and devices have been developed for the highly sensitive, selective, cost-effective, and rapid diagnosis of COVID-19. This review organizes the diagnosis platforms into four groups: imaging, molecular-based detection, serological testing, and biosensors. Each platform's principle, advancement, utilization, and challenges for monitoring SARS-CoV-2 are discussed in detail. In addition, an overview of the impact of variants on detection, commercially available kits, and readout signal analysis has been presented. This review will expand our understanding of developing advanced diagnostic approaches to evolve into susceptible, precise, and reproducible technologies to combat any future outbreak.

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