Incidence and Risk Factors of Postoperative Nausea and Vomiting in Lung Cancer Patients Following Lobectomy and Application of Analgesic Pumps

Overview

Journal J Int Med Res

Publisher Sage Publications

Specialty General Medicine

Date 2022 Jun 23

PMID 35735025

Authors

Suwen Wu

Chune Gan

Xiaoling Huang

Dongping Jiang

Ye Xu

Yixia Liao

Fen Ma

Yutong Hong

Hao Duan

Peng Lin

Affiliations

Soon will be listed here.

Abstract

Objective: To investigate the occurrence rate and risk factors of postoperative nausea and vomiting (PONV) in lung cancer patients following lobectomy and application of analgesic pumps.

Methods: This retrospective study reviewed clinical data from patients that had undergone lobectomy for lung cancer under general anaesthesia. The risk factors of PONV were analysed using binary logistic regression models.

Results: A total of 203 patients (97 females) were enrolled. The rate of PONV was 29.6% (60 of 203 patients) for all patients, 42.3% (41 of 97 patients) for female patients and 17.9% (19 of 106 patients) for male patients. Female patients undergoing thoracotomy (odds ratio [OR] 7.770, 95% confidence interval [CI] 1.747, 34.568) or having surgery durations ≥120 min (OR 4.493, 95% CI 1.502, 12.851) were significantly more susceptible to PONV. The risk of PONV in female patients that received postoperative dolasetron (100 mg, once a day) was significantly lower (OR 0.075, 95% CI 0.007, 0.834). For male patients, the risk of PONV was significantly lower in those with a body mass index ≥24 kg/m (OR 0.166; 95% CI 0.035, 0.782).

Conclusion: Female and male patients have different risk factors for PONV following lobectomy for lung cancer and application of analgesic pumps.

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