Management of Posterior Fossa Tumors in Adults Based on the Predictors of Postoperative Hydrocephalus

Overview

Journal Front Surg

Specialty General Surgery

Date 2022 Jun 20

PMID 35722528

Authors

Chengda Zhang

TingBao Zhang

Lingli Ge

Zhengwei Li

Jincao Chen

Affiliations

Soon will be listed here.

Abstract

Objective: This study aims to identify the predictors of postoperative hydrocephalus in patients with posterior fossa tumors (PFTs) and guide the management of perioperative hydrocephalus.

Methods: We performed a single-institution, retrospective analysis of patients who underwent resection of PFTs in our department over a 10-year period (2011-2021). A total of 682 adult patients met the inclusion criteria and were divided into either a prophylactic external ventricular drainage (EVD) group or a nonprophylactic-EVD group. We analyzed data for the nonprophylactic-EVD group by univariate and multivariate analyses to identify predictors of postoperative acute hydrocephalus. We also analyzed all cases by univariate and multivariate analyses to determine the predictors of postoperative ventriculoperitoneal (VP) shunt placement.

Results: Tumor infiltrating the midbrain aqueduct [ = 0.001; odds ratio (OR) = 9.8], postoperative hemorrhage ( < 0.001; OR = 66.7), and subtotal resection ( = 0.006; OR = 9.3) were independent risk factors for postoperative EVD. Tumor infiltrating the ventricular system ( < 0.001; OR = 58.5) and postoperative hemorrhage ( < 0.001; OR = 28.1) were independent risk factors for postoperative VP shunt placement.

Conclusions: These findings may help promote more aggressive monitoring and earlier interventions for postoperative hydrocephalus in patients with PFTs.

Citing Articles

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CLINICAL AND SURGICAL CHARACTERISTICS OF POSTERIOR FOSSA TUMORS IN ADULTS - SINGLE-CENTER EXPERIENCE OF SURGICAL MANAGEMENT.

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