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Atypical Legionnaires' Disease in the Setting of Suspected Recurrent Lung Cancer

Overview
Journal Cureus
Date 2022 Jun 10
PMID 35686263
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Abstract

Legionnaires' disease is a type of pneumonia caused by bacteria. This type of bacteria can be found anywhere across the world, mostly in moist environments (e.g., ground soil, rivers, lakes). More importantly, can multiply in water systems such as air conditioners, which is a common source of outbreaks nationwide, particularly during the summer months. We present a unique clinical course of Legionnaires' disease with suspected underlying recurrent lung cancer in a 77-year-old man during an outbreak that originated in a small city near our hospital. The patient presented to Urgent Care and after initial assessment, was admitted to the Internal Medicine Unit. He underwent supportive treatment with antibiotic therapy and oxygen, and was discharged one week after admission with improvement. The patient returned to Urgent Care a few weeks later with worsening dyspnea, where he was then transferred to another hospital for admission to the Intensive Care Unit (ICU), and later died. We report this special case to bring awareness to physicians of the possibility and importance of early detection and prompt management of Legionnaires' disease in lung cancer and critically ill patients with possible environmental risk factors. Prompt detection and management of L allows for a greater chance of a favorable prognosis, particularly in the immunocompromised.

References
1.
Fiumefreddo R, Zaborsky R, Haeuptle J, Christ-Crain M, Trampuz A, Steffen I . Clinical predictors for Legionella in patients presenting with community-acquired pneumonia to the emergency department. BMC Pulm Med. 2009; 9:4. PMC: 2636761. DOI: 10.1186/1471-2466-9-4. View

2.
Chahin A, Opal S . Severe Pneumonia Caused by Legionella pneumophila: Differential Diagnosis and Therapeutic Considerations. Infect Dis Clin North Am. 2017; 31(1):111-121. PMC: 7135102. DOI: 10.1016/j.idc.2016.10.009. View

3.
Heath C, Grove D, Looke D . Delay in appropriate therapy of Legionella pneumonia associated with increased mortality. Eur J Clin Microbiol Infect Dis. 1996; 15(4):286-90. DOI: 10.1007/BF01695659. View

4.
Newton H, Ang D, van Driel I, Hartland E . Molecular pathogenesis of infections caused by Legionella pneumophila. Clin Microbiol Rev. 2010; 23(2):274-98. PMC: 2863363. DOI: 10.1128/CMR.00052-09. View

5.
Fernandez-Sabe N, Roson B, Carratala J, Dorca J, Manresa F, Gudiol F . Clinical diagnosis of Legionella pneumonia revisited: evaluation of the Community-Based Pneumonia Incidence Study Group scoring system. Clin Infect Dis. 2003; 37(4):483-9. DOI: 10.1086/376627. View