Preparation of 4,15-diacetoxyscirpenol from Cultures of Fusarium Sambucinum NRRL 13495
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Microbiology
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Filtrates of Fusarium sambucinum NRRL 13495 grown in a stagnant culture for 9 days contained up to 458 +/- 60 (mean +/- standard error; n = 3) mg of 4,15-diacetoxyscirpenol per liter depending on culture conditions. Extraction with ethyl acetate, chromatography on a column of silica gel, and crystallization from mixtures of ethyl acetate and hexane provided pure material in 96% yield.
Diacetoxyscirpenol production by Fusarium sambucinum strain KF 735 on solid and liquid media.
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PMID: 23605734 DOI: 10.1007/BF03192181.
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PMID: 23605298 DOI: 10.1007/BF03192123.