The Effect of Transurethral Resection of the Prostate on Erectile and Ejaculatory Functions in Patients with Benign Prostatic Hyperplasia

Overview

Journal Urol Int

Publisher Karger

Specialty Urology

Date 2022 Jun 2

PMID 35654017

Authors

Saddam H Al Demour

Mohannad Abuhamad

Abdallah Nader Santarisi

Mohammad Al-Zubi

Samer Fathi Al-Rawashdah

Omar Halalsheh

Antonio Carbone

Antonio Luigi Pastore

Muayyad M Ahmad

Affiliations

Soon will be listed here.

Abstract

Introduction: The aim of this study was to investigate the effect of TURP on erectile function (EF) and ejaculatory function (EJF).

Methods: A total of 91 patients who underwent TURP were retrospectively assessed. Patients were divided into two groups based on International Index of Erectile Function (IIEF-5): group A included 41 patients with normal EF, and group B included 50 patients with erectile dysfunction (ED). All patients were evaluated for EF and EJF at baseline, 1, 3, and 6 months after TURP by using IIEF-5, Ejaculatory Domain-Male Sexual-Health Inventory (Ej-MSHQ).

Results: In group A, there were no significant statistical differences in mean IIEF-5 at baseline and after TURP 22.88 ± 0.81 versus 22.63 ± 2.63 (p = 0.065). However, in group B, there was significant improvement in IIEF-5 after TURP all over the follow-up time points in comparison to the baseline (p = <0.001). The loss of EJF was significant among patients in group A. There was significant improvement of IPSS and Qmax in group A after surgery compared to group B.

Conclusion: The results confirmed that TURP has no significant negative influence on EF, and patients with preexisting ED were improved after TURP. On the contrary, the loss of EJF was significant.

Citing Articles

Evaluating the Impact of Benign Prostatic Hyperplasia Surgical Treatments on Sexual Health.

Kaltsas A, Kratiras Z, Zachariou A, Dimitriadis F, Sofikitis N, Chrisofos M Biomedicines. 2024; 12(1).

PMID: 38255215 PMC: 10813562. DOI: 10.3390/biomedicines12010110.

References

Ahyai S, Gilling P, Kaplan S, Kuntz R, Madersbacher S, Montorsi F . Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement. Eur Urol. 2010; 58(3):384-97. DOI: 10.1016/j.eururo.2010.06.005. View

Choi S, Zhao C, Park J . The effect of transurethral resection of the prostate on erectile function in patients with benign prostatic hyperplasia. Korean J Urol. 2010; 51(8):557-60. PMC: 2924560. DOI: 10.4111/kju.2010.51.8.557. View

Becher E, McVary K . Surgical Procedures for BPH/LUTS: Impact on Male Sexual Health. Sex Med Rev. 2014; 2(1):47-55. DOI: 10.1002/smrj.20. View

Muntener M, Aellig S, Kuettel R, Gehrlach C, Sulser T, Strebel R . Sexual function after transurethral resection of the prostate (TURP): results of an independent prospective multicentre assessment of outcome. Eur Urol. 2007; 52(2):510-5. DOI: 10.1016/j.eururo.2007.01.088. View

Jaidane M, Arfa N, Hmida W, Hidoussi A, Slama A, Sorba N . Effect of transurethral resection of the prostate on erectile function: a prospective comparative study. Int J Impot Res. 2009; 22(2):146-51. DOI: 10.1038/ijir.2009.56. View

Borchert A, Leavitt D . A Review of Male Sexual Health and Dysfunction Following Surgical Treatment for Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms. Curr Urol Rep. 2018; 19(8):66. DOI: 10.1007/s11934-018-0813-0. View

Bruyere F, Puichaud A, Pereira H, Faivre dArcier B, Rouanet A, Floch A . Influence of photoselective vaporization of the prostate on sexual function: results of a prospective analysis of 149 patients with long-term follow-up. Eur Urol. 2010; 58(2):207-11. DOI: 10.1016/j.eururo.2010.04.027. View

Enikeev D, Glybochko P, Rapoport L, Okhunov Z, OLeary M, Potoldykova N . Impact of endoscopic enucleation of the prostate with thulium fiber laser on the erectile function. BMC Urol. 2018; 18(1):87. PMC: 6186032. DOI: 10.1186/s12894-018-0400-1. View

Vuichoud C, Loughlin K . Benign prostatic hyperplasia: epidemiology, economics and evaluation. Can J Urol. 2015; 22 Suppl 1:1-6. View

10.

Lerner L, McVary K, Barry M, Bixler B, Dahm P, Das A . Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA GUIDELINE PART II-Surgical Evaluation and Treatment. J Urol. 2021; 206(4):818-826. DOI: 10.1097/JU.0000000000002184. View

11.

Elshal A, Elmansy H, Elkoushy M, Elhilali M . Male sexual function outcome after three laser prostate surgical techniques: a single center perspective. Urology. 2012; 80(5):1098-104. DOI: 10.1016/j.urology.2012.08.001. View

12.

El-Assmy A, Elshal A, Mekkawy R, El-Kappany H, Ibrahiem E . Erectile and ejaculatory functions changes following bipolar versus monopolar transurethral resection of the prostate: a prospective randomized study. Int Urol Nephrol. 2018; 50(9):1569-1576. DOI: 10.1007/s11255-018-1950-6. View

13.

Kohler T, McVary K . The relationship between erectile dysfunction and lower urinary tract symptoms and the role of phosphodiesterase type 5 inhibitors. Eur Urol. 2008; 55(1):38-48. DOI: 10.1016/j.eururo.2008.08.062. View

14.

Rieken M, Antunes-Lopes T, Geavlete B, Marcelissen T . What Is New with Sexual Side Effects After Transurethral Male Lower Urinary Tract Symptom Surgery?. Eur Urol Focus. 2018; 4(1):43-45. DOI: 10.1016/j.euf.2018.05.001. View

15.

Poulakis V, Ferakis N, Witzsch U, de Vries R, Becht E . Erectile dysfunction after transurethral prostatectomy for lower urinary tract symptoms: results from a center with over 500 patients. Asian J Androl. 2005; 8(1):69-74. DOI: 10.1111/j.1745-7262.2006.00088.x. View

16.

Capogrosso P, Ventimiglia E, Ferrari M, Serino A, Boeri L, Capitanio U . Long-term sexual outcomes after holmium laser enucleation of the prostate: which patients could benefit the most?. Int J Impot Res. 2016; 28(5):189-93. DOI: 10.1038/ijir.2016.29. View

17.

Sturch P, Woo H, McNicholas T, Muir G . Ejaculatory dysfunction after treatment for lower urinary tract symptoms: retrograde ejaculation or retrograde thinking?. BJU Int. 2014; 115(2):186-7. DOI: 10.1111/bju.12868. View

18.

Hanbury D, Sethia K . Erectile function following transurethral prostatectomy. Br J Urol. 1995; 75(1):12-3. DOI: 10.1111/j.1464-410x.1995.tb07224.x. View

19.

Marra G, Sturch P, Oderda M, Tabatabaei S, Muir G, Gontero P . Systematic review of lower urinary tract symptoms/benign prostatic hyperplasia surgical treatments on men's ejaculatory function: Time for a bespoke approach?. Int J Urol. 2015; 23(1):22-35. DOI: 10.1111/iju.12866. View

20.

McMahon C, Abdo C, Incrocci L, Perelman M, Rowland D, Waldinger M . Disorders of orgasm and ejaculation in men. J Sex Med. 2006; 1(1):58-65. DOI: 10.1111/j.1743-6109.2004.10109.x. View