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Does Ileocecal Resection Affect Children's Medium-Long-Term Growth and Defecation Patterns? A Matched Case-Control Study

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Specialty Gastroenterology
Date 2022 Jun 1
PMID 35650462
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Abstract

Background: Ileocecal resection leads to some early complications, but it is unknown whether it affects children's medium-long-term growth and defecation patterns. To determine if there was an association, we conducted this matched case-control study.

Methods: This study was conducted in Beijing Children's Hospital and included three groups: the case group (n = 30) included patients with ileocecal duplication undergoing ileocecal resection between January 2010 and June 2021, the control group (n = 90) included outpatient patients without ileocecal resection in January 2022, and the appendectomy group (n = 90) included patients who underwent appendectomy between January 2010 and June 2021. The 1:1 matching criteria included gender and age (within 1 year). The evaluation indicators were growth (height-for-age, BMI) and defecation patterns (stool frequency, stool consistency) over 6 months after surgery. Defecation patterns were assessed in patients older than 4 years. Stool consistency was evaluated by the modified Bristol Stool Form Scale.

Results: There were no significant differences, except for stool consistency, between the case and control groups regarding their growth and defecation patterns before case-control matching. The patients in the case group had a significantly higher prevalence of dry stool (P < 0.008). After case-control matching, there were no significant differences in the growth and defecation patterns between the case and control groups. Before and after case-control matching, there were no significant differences in the defecation patterns between the control group and the appendectomy group.

Conclusion: Children's medium-long-term growth and defecation patterns were not affected by ileocecal resection.

References
1.
Cook L, Al-Hendawi E, Bates A, Brennan M, Salvestrini C, Malik M . Limited ileo-caecal resection for localised Crohn's disease in childhood: Clinical outcome and predictors of further surgery. J Crohns Colitis. 2010; 1(2):82-6. DOI: 10.1016/j.crohns.2007.08.003. View

2.
Strombeck A, Lasson A, Strid H, Sundin J, Stotzer P, Simren M . Fecal microbiota composition is linked to the postoperative disease course in patients with Crohn's disease. BMC Gastroenterol. 2020; 20(1):130. PMC: 7197162. DOI: 10.1186/s12876-020-01281-4. View

3.
Fasoli L, Turi R, Spitz L, Kiely E, Drake D, Pierro A . Necrotizing enterocolitis: extent of disease and surgical treatment. J Pediatr Surg. 1999; 34(7):1096-9. DOI: 10.1016/s0022-3468(99)90574-2. View

4.
Fisher J, Sparks E, Turner C, Klein J, Pennington E, Khan F . Operative indications in recurrent ileocolic intussusception. J Pediatr Surg. 2015; 50(1):126-30. DOI: 10.1016/j.jpedsurg.2014.10.012. View

5.
Jiang W, Xu X, Geng Q, Zhang J, Chen H, Lv X . Enteroenteroanastomosis near adjacent ileocecal valve in infants. World J Gastroenterol. 2013; 18(48):7314-8. PMC: 3544036. DOI: 10.3748/wjg.v18.i48.7314. View