Congress of Neurological Surgeons Systematic Review and Evidence-based Guidelines Update on the Role of Neuropathology in the Management of Progressive Glioblastoma in Adults
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Abstract
Target Population: These recommendations apply to adult patients with progressive or recurrent glioblastoma (GBM).
Question: For adult patients with progressive glioblastoma are there meaningful biomarkers for bevacizumab responsiveness and does their assessment provide additional information for tumor management and prognosis beyond that learned by standard histologic analysis?
Recommendation: Level III: No established Bevacizumab biomarkers are currently available based upon the inclusion criteria of this guideline.
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