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Globally Accessible Distributed Data Sharing (GADDS): a Decentralized FAIR Platform to Facilitate Data Sharing in the Life Sciences

Overview
Journal Bioinformatics
Specialty Biology
Date 2022 May 31
PMID 35639939
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Abstract

Motivation: Technical advances have revolutionized the life sciences and researchers commonly face challenges associated with handling large amounts of heterogeneous digital data. The Findable, Accessible, Interoperable and Reusable (FAIR) principles provide a framework to support effective data management. However, implementing this framework is beyond the means of most researchers in terms of resources and expertise, requiring awareness of metadata, policies, community agreements and other factors such as vocabularies and ontologies.

Results: We have developed the Globally Accessible Distributed Data Sharing (GADDS) platform to facilitate FAIR-like data-sharing in cross-disciplinary research collaborations. The platform consists of (i) a blockchain-based metadata quality control system, (ii) a private cloud-like storage system and (iii) a version control system. GADDS is built with containerized technologies, providing minimal hardware standards and easing scalability, and offers decentralized trust via transparency of metadata, facilitating data exchange and collaboration. As a use case, we provide an example implementation in engineered living material technology within the Hybrid Technology Hub at the University of Oslo.

Availability And Implementation: Demo version available at https://github.com/pavelvazquez/GADDS.

Supplementary Information: Supplementary data are available at Bioinformatics online.

References
1.
Wilkinson M, Dumontier M, Sansone S, Bonino da Silva Santos L, Prieto M, Batista D . Evaluating FAIR maturity through a scalable, automated, community-governed framework. Sci Data. 2019; 6(1):174. PMC: 6754447. DOI: 10.1038/s41597-019-0184-5. View

2.
Kodama Y, Shumway M, Leinonen R . The Sequence Read Archive: explosive growth of sequencing data. Nucleic Acids Res. 2011; 40(Database issue):D54-6. PMC: 3245110. DOI: 10.1093/nar/gkr854. View

3.
Wu Q, Liu J, Wang X, Feng L, Wu J, Zhu X . Organ-on-a-chip: recent breakthroughs and future prospects. Biomed Eng Online. 2020; 19(1):9. PMC: 7017614. DOI: 10.1186/s12938-020-0752-0. View

4.
Wilkinson M, Dumontier M, Aalbersberg I, Appleton G, Axton M, Baak A . The FAIR Guiding Principles for scientific data management and stewardship. Sci Data. 2016; 3:160018. PMC: 4792175. DOI: 10.1038/sdata.2016.18. View

5.
Eisenstein M . In pursuit of data immortality. Nature. 2022; 604(7904):207-208. DOI: 10.1038/d41586-022-00929-3. View