The Impact of Cognitive Behavioral Therapy on Peripheral Interleukin-6 Levels in Depression: A Systematic Review and Meta-Analysis

Overview

Journal Front Psychiatry

Specialty Psychiatry

Date 2022 May 31

PMID 35633813

Authors

Haijing Ma

Jiatong Xu

Ruonan Li

Roger S McIntyre

Kayla M Teopiz

Bing Cao

Fahui Yang

Affiliations

Soon will be listed here.

Abstract

Systematic Review Registration: https://doi.org/10.17605/osf.io/tr9yh, identifier: 10.17605/osf.io/tr9yh.

Citing Articles

Understanding immune system dysfunction and its context in mood disorders: psychoneuroimmunoendocrinology and clinical interventions.

Ortega M, Fraile-Martinez O, Garcia-Montero C, Diaz-Pedrero R, Lopez-Gonzalez L, Monserrat J Mil Med Res. 2024; 11(1):80.

PMID: 39681901 PMC: 11650850. DOI: 10.1186/s40779-024-00577-w.

Algorithm-Based Modular Psychotherapy Alleviates Brain Inflammation in Generalized Anxiety Disorder.

Keri S, Kancsev A, Kelemen O Life (Basel). 2024; 14(7).

PMID: 39063640 PMC: 11278507. DOI: 10.3390/life14070887.

Inflammatory markers changes following acceptance-based behavioral psychotherapy in generalized anxiety disorder patients: Evidence from a randomized controlled trial.

Gandarela L, de A Sampaio T, Marcal L, Burdmann E, Neto F, Bernik M Brain Behav Immun Health. 2024; 38:100779.

PMID: 38725444 PMC: 11081778. DOI: 10.1016/j.bbih.2024.100779.

Potential Inflammatory Biomarkers for Major Depressive Disorder Related to Suicidal Behaviors: A Systematic Review.

Kim K, Shin K, Chang K Int J Mol Sci. 2023; 24(18).

PMID: 37762207 PMC: 10531013. DOI: 10.3390/ijms241813907.

How Oxidative Stress Induces Depression?.

Ji N, Lei M, Chen Y, Tian S, Li C, Zhang B ASN Neuro. 2023; 15:17590914231181037.

PMID: 37331994 PMC: 10280786. DOI: 10.1177/17590914231181037.

References

Irwin M, Miller A . Depressive disorders and immunity: 20 years of progress and discovery. Brain Behav Immun. 2007; 21(4):374-83. DOI: 10.1016/j.bbi.2007.01.010. View

Maes M, Scharpe S, Meltzer H, Bosmans E, Suy E, Calabrese J . Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression. Psychiatry Res. 1993; 49(1):11-27. DOI: 10.1016/0165-1781(93)90027-e. View

Kang D, McArdle T, Park N, Weaver M, Smith B, Carpenter J . Dose effects of relaxation practice on immune responses in women newly diagnosed with breast cancer: an exploratory study. Oncol Nurs Forum. 2011; 38(3):E240-52. DOI: 10.1188/11.ONF.E240-E252. View

Rothermundt M, Arolt V, Fenker J, Gutbrodt H, Peters M, Kirchner H . Different immune patterns in melancholic and non-melancholic major depression. Eur Arch Psychiatry Clin Neurosci. 2001; 251(2):90-7. DOI: 10.1007/s004060170058. View

Huppert J . The building blocks of treatment in cognitive-behavioral therapy. Isr J Psychiatry Relat Sci. 2010; 46(4):245-50. View

Chen Y, Lin W, Chen Y, Mao W, Hung Y . Antidepressant effects on insulin sensitivity and proinflammatory cytokines in the depressed males. Mediators Inflamm. 2010; 2010:573594. PMC: 2872762. DOI: 10.1155/2010/573594. View

Smith K, Au B, Ollis L, Schmitz N . The association between C-reactive protein, Interleukin-6 and depression among older adults in the community: A systematic review and meta-analysis. Exp Gerontol. 2017; 102:109-132. DOI: 10.1016/j.exger.2017.12.005. View

Dunjic-Kostic B, Ivkovic M, Radonjic N, Petronijevic N, Pantovic M, Damjanovic A . Melancholic and atypical major depression--connection between cytokines, psychopathology and treatment. Prog Neuropsychopharmacol Biol Psychiatry. 2012; 43:1-6. DOI: 10.1016/j.pnpbp.2012.11.009. View

Moore R, Chattillion E, Ceglowski J, Ho J, von Kanel R, Mills P . A randomized clinical trial of Behavioral Activation (BA) therapy for improving psychological and physical health in dementia caregivers: results of the Pleasant Events Program (PEP). Behav Res Ther. 2013; 51(10):623-32. PMC: 3774137. DOI: 10.1016/j.brat.2013.07.005. View

10.

Lanquillon S, Krieg J, Bening-Abu-Shach U, Vedder H . Cytokine production and treatment response in major depressive disorder. Neuropsychopharmacology. 2000; 22(4):370-9. DOI: 10.1016/S0893-133X(99)00134-7. View

11.

Karlovic D, Serretti A, Marcinko D, Martinac M, Silic A, Katinic K . Serum testosterone concentration in combat-related chronic posttraumatic stress disorder. Neuropsychobiology. 2012; 65(2):90-5. DOI: 10.1159/000329556. View

12.

Parker G, Roy K, Eyers K . Cognitive behavior therapy for depression? Choose horses for courses. Am J Psychiatry. 2003; 160(5):825-34. DOI: 10.1176/appi.ajp.160.5.825. View

13.

Rosenblat J, Cha D, Mansur R, McIntyre R . Inflamed moods: a review of the interactions between inflammation and mood disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2014; 53:23-34. DOI: 10.1016/j.pnpbp.2014.01.013. View

14.

Hiles S, Baker A, de Malmanche T, Attia J . A meta-analysis of differences in IL-6 and IL-10 between people with and without depression: exploring the causes of heterogeneity. Brain Behav Immun. 2012; 26(7):1180-8. DOI: 10.1016/j.bbi.2012.06.001. View

15.

Lee Y, Mansur R, Brietzke E, Kapogiannis D, Delgado-Peraza F, Boutilier J . Peripheral inflammatory biomarkers define biotypes of bipolar depression. Mol Psychiatry. 2021; 26(7):3395-3406. PMC: 8413393. DOI: 10.1038/s41380-021-01051-y. View

16.

An H, He R, Zheng Y, Tao R . Cognitive-Behavioral Therapy. Adv Exp Med Biol. 2017; 1010:321-329. DOI: 10.1007/978-981-10-5562-1_16. View

17.

Beurel E, Toups M, Nemeroff C . The Bidirectional Relationship of Depression and Inflammation: Double Trouble. Neuron. 2020; 107(2):234-256. PMC: 7381373. DOI: 10.1016/j.neuron.2020.06.002. View

18.

Guyatt G, Oxman A, Vist G, Kunz R, Falck-Ytter Y, Alonso-Coello P . GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008; 336(7650):924-6. PMC: 2335261. DOI: 10.1136/bmj.39489.470347.AD. View

19.

Zautra A, Davis M, Reich J, Nicassario P, Tennen H, Finan P . Comparison of cognitive behavioral and mindfulness meditation interventions on adaptation to rheumatoid arthritis for patients with and without history of recurrent depression. J Consult Clin Psychol. 2008; 76(3):408-421. DOI: 10.1037/0022-006X.76.3.408. View

20.

Dalkner N, Reininghaus E, Schwalsberger K, Rieger A, Hamm C, Pilz R . C-Reactive Protein as a Possible Predictor of Trail-Making Performance in Individuals with Psychiatric Disorders. Nutrients. 2020; 12(10). PMC: 7599970. DOI: 10.3390/nu12103019. View