Engineering Gold Nanostructures for Cancer Treatment: Spherical Nanoparticles, Nanorods, and Atomically Precise Nanoclusters
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Cancer is a major global health issue and is a leading cause of mortality. It has been documented that various conventional treatments can be enhanced by incorporation with nanomaterials. Thanks to their rich optical properties, excellent biocompatibility, and tunable chemical reactivities, gold nanostructures have been gaining more and more research attention for cancer treatment in recent decades. In this review, we first summarize the recent progress in employing three typical gold nanostructures, namely spherical Au nanoparticles, Au nanorods, and atomically precise Au nanoclusters, for cancer diagnostics and therapeutics. Following that, the challenges and the future perspectives of this field are discussed. Finally, a brief conclusion is summarized at the end.
Justo-Tirado M, Perez-Herraez I, Escorihuela J, Arenal R, Zaballos-Garcia E, Perez-Prieto J Nanoscale Adv. 2024; .
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The quest for nanoparticle-powered vaccines in cancer immunotherapy.
Sun Z, Zhao H, Ma L, Shi Y, Ji M, Sun X J Nanobiotechnology. 2024; 22(1):61.
PMID: 38355548 PMC: 10865557. DOI: 10.1186/s12951-024-02311-z.
pH-Dependent HEWL-AuNPs Interactions: Optical Study.
Molkova E, Pustovoy V, Stepanova E, Gorudko I, Astashev M, Simakin A Molecules. 2024; 29(1).
PMID: 38202662 PMC: 10779547. DOI: 10.3390/molecules29010082.
New insights into nanosystems for non-small-cell lung cancer: diagnosis and treatment.
Jiang P, Liang B, Zhang Z, Fan B, Zeng L, Zhou Z RSC Adv. 2023; 13(28):19540-19564.
PMID: 37388143 PMC: 10300523. DOI: 10.1039/d3ra03099g.
Zhang J, Yin J, Lai R, Wang Y, Mao B, Wu H Nanomaterials (Basel). 2023; 13(6).
PMID: 36985918 PMC: 10059579. DOI: 10.3390/nano13061024.