DYN-1/dynamin Regulates Microtubule Dynamics After Axon Injury

Overview

Journal MicroPubl Biol

Specialty Biology

Date 2022 May 27

PMID 35622508

Authors

Tarika Vijayaraghavan

Samiksha Dhananjay

Brent Neumann

Affiliations

Soon will be listed here.

References

Scaife R, Margolis R . Biochemical and immunochemical analysis of rat brain dynamin interaction with microtubules and organelles in vivo and in vitro. J Cell Biol. 1990; 111(6 Pt 2):3023-33. PMC: 2116430. DOI: 10.1083/jcb.111.6.3023. View

Neumann B, Linton C, Giordano-Santini R, Hilliard M . Axonal fusion: An alternative and efficient mechanism of nerve repair. Prog Neurobiol. 2018; 173:88-101. DOI: 10.1016/j.pneurobio.2018.11.004. View

Herskovits J, Shpetner H, Burgess C, Vallee R . Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain. Proc Natl Acad Sci U S A. 1993; 90(24):11468-72. PMC: 48005. DOI: 10.1073/pnas.90.24.11468. View

Blanquie O, Bradke F . Cytoskeleton dynamics in axon regeneration. Curr Opin Neurobiol. 2018; 51:60-69. DOI: 10.1016/j.conb.2018.02.024. View

Shpetner H, Vallee R . Dynamin is a GTPase stimulated to high levels of activity by microtubules. Nature. 1992; 355(6362):733-5. DOI: 10.1038/355733a0. View

Chen L, Chuang M, Koorman T, Boxem M, Jin Y, Chisholm A . Axon injury triggers EFA-6 mediated destabilization of axonal microtubules via TACC and doublecortin like kinase. Elife. 2015; 4. PMC: 4596636. DOI: 10.7554/eLife.08695. View

Chen L . Microtubules and axon regeneration in C. elegans. Mol Cell Neurosci. 2018; 91:160-166. DOI: 10.1016/j.mcn.2018.03.007. View

Chisholm A, Hutter H, Jin Y, Wadsworth W . The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans. Genetics. 2017; 204(3):849-882. PMC: 5105865. DOI: 10.1534/genetics.115.186262. View

Yanik M, Cinar H, Cinar H, Chisholm A, Jin Y, Ben-Yakar A . Neurosurgery: functional regeneration after laser axotomy. Nature. 2004; 432(7019):822. DOI: 10.1038/432822a. View

10.

Chen L, Wang Z, Ghosh-Roy A, Hubert T, Yan D, ORourke S . Axon regeneration pathways identified by systematic genetic screening in C. elegans. Neuron. 2011; 71(6):1043-57. PMC: 3183436. DOI: 10.1016/j.neuron.2011.07.009. View

11.

Brenner S . The genetics of Caenorhabditis elegans. Genetics. 1974; 77(1):71-94. PMC: 1213120. DOI: 10.1093/genetics/77.1.71. View

12.

Neumann B, Hilliard M . Loss of MEC-17 leads to microtubule instability and axonal degeneration. Cell Rep. 2013; 6(1):93-103. PMC: 3939029. DOI: 10.1016/j.celrep.2013.12.004. View

13.

Ghosh-Roy A, Goncharov A, Jin Y, Chisholm A . Kinesin-13 and tubulin posttranslational modifications regulate microtubule growth in axon regeneration. Dev Cell. 2012; 23(4):716-28. PMC: 3477258. DOI: 10.1016/j.devcel.2012.08.010. View

14.

Abay Z, Wong M, Teoh J, Vijayaraghavan T, Hilliard M, Neumann B . Phosphatidylserine save-me signals drive functional recovery of severed axons in . Proc Natl Acad Sci U S A. 2017; 114(47):E10196-E10205. PMC: 5703272. DOI: 10.1073/pnas.1703807114. View

15.

Shpetner H, Vallee R . Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules. Cell. 1989; 59(3):421-32. DOI: 10.1016/0092-8674(89)90027-5. View