The Potential Role of RNA Structure in Crop Molecular Breeding

Overview

Journal Front Plant Sci

Date 2022 May 19

PMID 35586218

Authors

Wenqing Sun

Ling Ding

Huakun Zhang

Affiliations

Soon will be listed here.

Abstract

The continually growing human population creates a concomitantly increasing demand for nutritious crops with high yields. Advances in high throughput sequencing technologies have revealed the genetic architecture of major crops. This includes extensive information enabling comprehensive genetic markers for breeding selection, new gene discoveries, and novel gene regulatory strategies for crop editing. RNA structure is an important type of genetic feature, essential for post-transcriptional regulation of gene expression. Here, we summarize recent advances in genome-wide RNA structure studies in crops and review the associated RNA structure-mediated regulation of gene expression. We also discuss the functional importance of those single nucleotide variations that induce large RNA structure disparities. Lastly, we discuss the potential role of RNA structure in crop molecular breeding.

Citing Articles

Identification of RNA structures and their roles in RNA functions.

Cao X, Zhang Y, Ding Y, Wan Y Nat Rev Mol Cell Biol. 2024; 25(10):784-801.

PMID: 38926530 DOI: 10.1038/s41580-024-00748-6.

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