Stroke in Sickle Cell Disease in Association with Bilateral Absence of the Internal Carotid Arteries. Case Report

Overview

Journal BMC Neurol

Publisher Biomed Central

Specialty Neurology

Date 2022 May 17

PMID 35581570

Authors

Ivana Markovic

Zoran Milenkovic

Bosanka Jocic-Jakubi

Amna Al Futaisi

Kakaria Anupam Kakaria

Yasser Walli

Affiliations

Soon will be listed here.

Abstract

Background: Congenital absence of the internal carotid artery (ICA) is a highly infrequent congenital incidence and occurs in less than 0.01% of the population; bilateral absence is exceedingly rare, diagnosed below 10% of the unilateral absence of the ICA. Sickle cell disease (SCD) is a serious disorder and carries a high risk of stroke.

Case Presentation: We present a five-year-old child with SCD who experienced an ischemic stroke episode with epileptic seizures. Neuroimaging revealed the agenesis of both ICAs. The frequency, embryology, and collateral pathway of the vascular anomaly as the clinical presentation, of this rare hematologic disease, are discussed.

Conclusions: Sickle cell disease (SCD) carries a high risk of stroke. Congenital absence of ICA occurs in less than 0.01% of the population; bilateral absence is diagnosed below 10% of the unilateral absence of the ICA.

Citing Articles

Bilateral internal carotid artery agenesis coexisting with bovine aortic arch: case report and literature review.

Elqasass A, Hobeika L, Al-Dawoud Y, Aldarras M, Yousef H, Al Ryalat N Anat Sci Int. 2024; 100(1):15-24.

PMID: 39230857 DOI: 10.1007/s12565-024-00795-1.

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