Voriconazole- Induced Severe Hypokalemic Rhabdomyolysis: A Case Report

Overview

Journal Int J Pediatr Adolesc Med

Date 2022 May 16

PMID 35573070

Authors

Abdulsalam Alawfi

Abdullah Algarni

Jocelyn Donesa

Motasem Abuelreish

Affiliations

Soon will be listed here.

Abstract

We report a child who presented with lower limb weakness and inability to walk, laboratory confirmed severe hypokalemia with typical electrocardiogram changes, and evidence of rhabdomyolysis while on voriconazole treatment for soft tissue infection. Although voriconazole is a well-tolerated antifungal agent, hypokalemia is a well-known, yet uncommon side effect associated with its use. Furthermore, hypokalemic-rhabdomyolysis has not been reported with voriconazole use alone. Maintaining the clinical suspicion about the potential association between voriconazole and hypokalemic-rhabdomyolysis can lead to prompt recognition and intervention.

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