Alkene Hydroboration with Pinacolborane Catalysed by Lithium Diisobutyl--butoxyaluminum Hydride

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2022 May 9

PMID 35530999

Authors

Ashok Kumar Jaladi

Won Kyu Shin

Duk Keun An

Affiliations

Soon will be listed here.

Abstract

Here we developed a highly efficient alkene hydroboration protocol, showing that various alkyl boronates can be smoothly obtained in good yields by reacting alkenes with pinacolborane (HBpin) in the presence of 5 mol% lithium diisobutyl--butoxyaluminum hydride. The coordination of aluminate ions with lithium cations allowed for effective hydride transfer during hydroboration, and the obtained boronate ester was further used for C-C coupling, trifluoroboronate salt formation, and oxidation to alcohol.

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