Correlation Between Lipophilicity of Newly Synthesized Ionic Liquids and Selected Genus Growth Rate

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2022 May 6

PMID 35516878

Authors

Milan Vranes

Aleksandar Tot

Jasenka Cosic

Snezana Papovic

Jovana Panic

Slobodan Gadzuric

Nenad Jankovic

Karolina Vrandecic

Affiliations

Soon will be listed here.

Abstract

The purpose of the present study was to examine the effectiveness of 23 different synthesized ionic liquids (ILs) on and growth rate. The strategy of IL synthesis was a structural modification of ionic liquids through changing the polarity of imidazolium and pycolinium cations and replacing halide anions with well known antifungal anions (cinnamate, caffeate and mandelate). The findings clearly suggest that the type of alkyl chain on the cation is the most determining factor for IL toxicity. In order to examine how IL structure affects their toxicity towards genus, lipophilic descriptor log is calculated from density functional theory and correlated with growth rate. All these results demonstrate the high level of the interdependency of lipophilicity and toxicity for investigated ILs towards the genus. The data collected in this research suggest that the inhibitory influence of ILs is more pronounced in the case of .

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