Synthesis of Hierarchically Mesoporous Silica with Encapsulated Avobenzone As a UV Protection Filter

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2022 May 2

PMID 35493675

Authors

Wei-Hsun Wang

Hsin-Tung Liang

Yuan-Ting Yang-Wang

Chi-Jen Shih

Affiliations

Soon will be listed here.

Abstract

In this study, hierarchically mesoporous silica (HMS) with properties such as high specific surface area, high photostability, and no cellular toxicity was synthesized. The synthesized silica can be considered as an excellent carrier candidate material. Through the use of nitrogen adsorption and desorption analysis, the shape of the hysteresis loop implied the presence of mesoporous structures in the HMS powder. In addition, the encapsulation efficiency was more than 90%. These results showed that avobenzone could be encapsulated into the HMS powder because of its high specific surface area and pore volume. Additionally, X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA), and UV-visible (Vis) spectrophotometry were used to prove that the hierarchically mesoporous silica was able to effectively encapsulate avobenzone. In addition, the new synthetic sunscreen kept its excellent UVA absorption properties after being encapsulated.

Citing Articles

Drug Delivery Strategies for Avobenzone: A Case Study of Photostabilization.

Gholap A, Sayyad S, Hatvate N, Dhumal V, Pardeshi S, Chavda V Pharmaceutics. 2023; 15(3).

PMID: 36986867 PMC: 10059943. DOI: 10.3390/pharmaceutics15031008.

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