» Articles » PMID: 35492380

Visceral Adipose Tissue Influence on Health Problem Development and Its Relationship with Serum Biochemical Parameters in Middle-Aged and Older Adults: A Literature Review

Overview
Journal J Aging Res
Publisher Wiley
Specialty Geriatrics
Date 2022 May 2
PMID 35492380
Authors
Affiliations
Soon will be listed here.
Abstract

Background: The amount of visceral adipose tissue (VAT) tends to increase with age and is associated with several health problems, such as cardiometabolic diseases, increased infections, and overall mortality.

Objectives: This review provides a general assessment of how visceral adiposity correlates with the development of health problems and changes in serum biochemical parameters in middle-aged and older adults.

Methods: We searched specific terms in the Virtual Health Library (VHL) databases for VAT articles published in the English language between 2009 and 2019 related to older adults.

Results: The search found twenty-three publications in this period, of which nine were excluded. The publications had a population aged between 42 and 83 years and correlated the VAT area ratio with several comorbidities (such as pancreatitis, depression, cancer, and coronary heart disease) and serum biochemical parameters.

Conclusion: Further research on the association between visceral obesity and the emergence of health problems and the relationship between VAT and changes in serum biochemical parameters in older individuals should deepen the understanding of this connection and develop preventive actions.

Citing Articles

Association between sarcopenia and weight-adjusted waist index in male patients with type 2 diabetes.

Xiang Y, Wang Z, Xu J, Wang J, Wu C, Pan Y BMC Endocr Disord. 2025; 25(1):20.

PMID: 39863834 PMC: 11765918. DOI: 10.1186/s12902-025-01846-y.


Suppression of the postprandial hyperglycemia in patients with type 2 diabetes by a raw medicinal herb powder is weakened when consumed in ordinary hard gelatin capsules: A randomized crossover clinical trial.

Moreira F, Reis C, Gallassi A, Moreira D, Welker A PLoS One. 2024; 19(10):e0311501.

PMID: 39383145 PMC: 11463819. DOI: 10.1371/journal.pone.0311501.


Machine learning allows robust classification of visceral fat in women with obesity using common laboratory metrics.

Palmieri F, Akhtar N, Pane A, Jimenez A, Olbeyra R, Viaplana J Sci Rep. 2024; 14(1):17263.

PMID: 39068287 PMC: 11283481. DOI: 10.1038/s41598-024-68269-y.

References
1.
Kim T, Choi K . The implications of sarcopenia and sarcopenic obesity on cardiometabolic disease. J Cell Biochem. 2014; 116(7):1171-8. DOI: 10.1002/jcb.25077. View

2.
Sugimoto M, Farnell M, Nagorney D, Kendrick M, Truty M, Smoot R . Decreased Skeletal Muscle Volume Is a Predictive Factor for Poorer Survival in Patients Undergoing Surgical Resection for Pancreatic Ductal Adenocarcinoma. J Gastrointest Surg. 2018; 22(5):831-839. PMC: 6057620. DOI: 10.1007/s11605-018-3695-z. View

3.
Falchi M, El-Sayed Moustafa J, Takousis P, Pesce F, Bonnefond A, Andersson-Assarsson J . Low copy number of the salivary amylase gene predisposes to obesity. Nat Genet. 2014; 46(5):492-7. PMC: 6485469. DOI: 10.1038/ng.2939. View

4.
Taylor A, Bindeman J, Feuerstein I, Cao F, Brazaitis M, OMalley P . Coronary calcium independently predicts incident premature coronary heart disease over measured cardiovascular risk factors: mean three-year outcomes in the Prospective Army Coronary Calcium (PACC) project. J Am Coll Cardiol. 2005; 46(5):807-14. DOI: 10.1016/j.jacc.2005.05.049. View

5.
Webber B, Seguin P, Burnett D, Clark L, Otto J . Prevalence of and risk factors for autopsy-determined atherosclerosis among US service members, 2001-2011. JAMA. 2012; 308(24):2577-83. DOI: 10.1001/jama.2012.70830. View