[Optimization of an Integrated Approach to Voice Correction for Endocrinopathies (analytical Review)]

Overview

Journal Probl Endokrinol (Mosk)

Specialty Endocrinology

Date 2022 Apr 30

PMID 35488756

Authors

S V Starostina

Ya A Statsenko

V M Svistushkin

Affiliations

Soon will be listed here.

Abstract

Dysphonia is a symptom of many endocrine pathologies. Hoarseness, voice fatigue, decrease of the voice pitch, reduce of the range are typical complaints for hypothyroidism, caused by an increased amount of polysaccharides and accumulation of fluid in the lamina propria of the vocal folds. An excess of growth hormone causes an overproduction of insulin-like growth factor-1, which leads to abnormalities in the craniofacial region and proliferation of the upper respiratory tract tissues, including thickening of the laryngeal cartilages, vocal folds and decreasing of the voice pitch. Hyperglycemia, changes in the balance of fluid and electrolytes in diabetes mellitus can indirectly affect the voice: xerostomia complicates phonation due to impaired hydration of the laryngeal mucosa, diabetic neuropathy often disrupts the work of the laryngeal muscles involved in voice formation. Voice changes are observed not only in endocrine disorders, but also during puberty, the phases of the menstrual cycle and during menopause. Laryngeal structures are modified under the influence of hormones and external factors, which generally changes pitch and intensity of the voice, timbre and resonance, articulation and prosodic characteristics. The purpose of this review is to summarize and systematize data on physiological and pathological voice changes in patients of different age groups and sex. The possibilities of a multidisciplinary approach to rational voice correction are demonstrated.

References

Saboor Aftab S, Kumar S, Barber T . The role of obesity and type 2 diabetes mellitus in the development of male obesity-associated secondary hypogonadism. Clin Endocrinol (Oxf). 2012; 78(3):330-7. DOI: 10.1111/cen.12092. View

Viana Baptista S, Lott D, Almeida S, Cid M, Vera-Cruz P, Zagalo C . Preoperative Voice Characteristics in Thyroid Patients. J Voice. 2020; 35(5):809.e1-809.e6. DOI: 10.1016/j.jvoice.2019.12.024. View

El-Shafie K . Hypothyroidism presenting with dysarthria. J Family Community Med. 2012; 10(2):55-7. PMC: 3425768. View

Mortimore I, Marshall I, Wraith P, Sellar R, Douglas N . Neck and total body fat deposition in nonobese and obese patients with sleep apnea compared with that in control subjects. Am J Respir Crit Care Med. 1998; 157(1):280-3. DOI: 10.1164/ajrccm.157.1.9703018. View

Aydin K, Akbulut S, Demir M, Demir S, Ozderya A, Temizkan S . Voice characteristics associated with polycystic ovary syndrome. Laryngoscope. 2015; 126(9):2067-72. DOI: 10.1002/lary.25818. View

Hamdan A, Kurban Z, Azar S . Prevalence of phonatory symptoms in patients with type 2 diabetes mellitus. Acta Diabetol. 2012; 50(5):731-6. DOI: 10.1007/s00592-012-0392-3. View

Lim J, Lim S, Choi S, Kim J, Kim K, Choi H . Clinical characteristics and voice analysis of patients with mutational dysphonia: clinical significance of diplophonia and closed quotients. J Voice. 2006; 21(1):12-9. DOI: 10.1016/j.jvoice.2005.10.002. View

Bellantone R, Lombardi C, Bossola M, Boscherini M, De Crea C, Alesina P . Total thyroidectomy for management of benign thyroid disease: review of 526 cases. World J Surg. 2002; 26(12):1468-71. DOI: 10.1007/s00268-002-6426-1. View

Nam I, Park Y . Pharyngolaryngeal symptoms associated with thyroid disease. Curr Opin Otolaryngol Head Neck Surg. 2017; 25(6):469-474. DOI: 10.1097/MOO.0000000000000404. View

10.

Chandrasekhar S, Randolph G, Seidman M, Rosenfeld R, Angelos P, Barkmeier-Kraemer J . Clinical practice guideline: improving voice outcomes after thyroid surgery. Otolaryngol Head Neck Surg. 2013; 148(6 Suppl):S1-37. DOI: 10.1177/0194599813487301. View

11.

Bartsch D, Dotzenrath C, Vorlander C, Zielke A, Weber T, Buhr H . Current Practice of Surgery for Benign Goitre-An Analysis of the Prospective DGAV StuDoQ|Thyroid Registry. J Clin Med. 2019; 8(4). PMC: 6517925. DOI: 10.3390/jcm8040477. View

12.

Ghaemi H, Dehqan A, Mahmoodi-Bakhtiari B, Scherer R . Voice Changes During Pregnancy Trimesters in Iranian Pregnant Women. J Voice. 2018; 34(3):358-363. DOI: 10.1016/j.jvoice.2018.09.016. View

13.

Haugen B, Alexander E, Bible K, Doherty G, Mandel S, Nikiforov Y . 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2015; 26(1):1-133. PMC: 4739132. DOI: 10.1089/thy.2015.0020. View

14.

Shilenkova V, Bestolkova O . [Presbiphonia. Age-related changes in the acoustic voice characteristics]. Vestn Otorinolaringol. 2014; (6):24-7. View

15.

Stollberger C, Finsterer J, Brand E, Tschabitscher D . Dysarthria as the leading symptom of hypothyroidism. Am J Otolaryngol. 2001; 22(1):70-2. DOI: 10.1053/ajot.2001.20698. View

16.

Voelter C, Kleinsasser N, Joa P, Nowack I, Martinez R, Hagen R . Detection of hormone receptors in the human vocal fold. Eur Arch Otorhinolaryngol. 2008; 265(10):1239-44. DOI: 10.1007/s00405-008-0632-x. View

17.

Gugatschka M, Lichtenwagner S, Schwetz V, Lerchbaum E, Graupp M, Gerstenberger C . Subjective and objective vocal parameters in women with polycystic ovary syndrome. J Voice. 2012; 27(1):98-100. DOI: 10.1016/j.jvoice.2012.07.007. View

18.

Starostina S, Mareev O, Nikolenko V . [Mediafixation of the vocal cord through the external approach in the patients presenting with unilateral laryngeal paralysis]. Vestn Otorinolaringol. 2014; (6):51-4. View

19.

Hannoun A, Zreik T, Tanbouzi Husseini S, Mahfoud L, Sibai A, Hamdan A . Vocal changes in patients with polycystic ovary syndrome. J Voice. 2010; 25(4):501-4. DOI: 10.1016/j.jvoice.2009.12.005. View

20.

Karpova O, Svistushkin V . [The modern approach to the conservative treatment of the patients presenting with postoperative bilateral vocal fold palsy]. Vestn Otorinolaringol. 2017; 82(1):25-29. DOI: 10.17116/otorino201782125-29. View