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Bacteremia During COVID-19 Pandemic in a Tertiary Hospital in Spain

Overview
Journal Enferm Infecc Microbiol Clin (Engl Ed)
Specialties Infectious Diseases
Microbiology
Date 2022 Apr 27
PMID 35473989
Authors
Saray Mormeneo Bayo
Maria Pilar Palacian Ruiz
Miguel Moreno Hijazo
Maria Cruz Villuendas Uson
Affiliations
Soon will be listed here.
Abstract

Introduction: The reasons for the decrease in blood cultures were investigated and the rate and aetiology of bacteremia and contaminated blood cultures collected from COVID and non-COVID patients were assessed.

Methods: We performed a retrospective analysis in a tertiary hospital in Spain during the COVID period from 4th March 2020 to 21st June 2020.

Results: The number of blood cultures processed was 5313, representing 22.7% and 18.8% of decrease compared to the same months of 2019 and 2018, respectively (p=0.173). The rate of bacteremia was 1.2% higher among COVID-patients than among non-COVID patients (p<0.001). COVID patients had a higher proportion of nosocomial bacteremia (95.5%) than non-COVID patients (30.5%) (p<0.001). In COVID-positive patients, the contamination rate was 12.3% vs 5.7% in non-COVID patients (p<0.001).

Conclusion: There was a decrease in the number of blood cultures collected during the COVID period compared to previous years. Bacteremia in COVID patients was mainly nosocomial and catheter-related.

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References
1.
Candel F, Borges Sa M, Belda S, Bou G, Del Pozo J, Estrada O . Current aspects in sepsis approach. Turning things around. Rev Esp Quimioter. 2018; 31(4):298-315. PMC: 6172679. View
2.
Dargere S, Cormier H, Verdon R . Contaminants in blood cultures: importance, implications, interpretation and prevention. Clin Microbiol Infect. 2018; 24(9):964-969. DOI: 10.1016/j.cmi.2018.03.030. View
3.
Hughes S, Troise O, Donaldson H, Mughal N, Moore L . Bacterial and fungal coinfection among hospitalized patients with COVID-19: a retrospective cohort study in a UK secondary-care setting. Clin Microbiol Infect. 2020; 26(10):1395-1399. PMC: 7320692. DOI: 10.1016/j.cmi.2020.06.025. View
4.
Sepulveda J, Westblade L, Whittier S, Satlin M, Greendyke W, Aaron J . Bacteremia and Blood Culture Utilization during COVID-19 Surge in New York City. J Clin Microbiol. 2020; 58(8). PMC: 7383550. DOI: 10.1128/JCM.00875-20. View
5.
Ozma M, Maroufi P, Khodadadi E, Kose S, Esposito I, Ganbarov K . Clinical manifestation, diagnosis, prevention and control of SARS-CoV-2 (COVID-19) during the outbreak period. Infez Med. 2020; 28(2):153-165. View