Treatment of Placenta Increta With High-Intensity Focused Ultrasound Ablation and Leaving the Placenta : A Multicenter Comparative Study

Overview

Journal Front Med (Lausanne)

Specialty General Medicine

Date 2022 Apr 25

PMID 35463039

Authors

Xiaoping Guan

Xiaoqin Huang

Min Ye

Guohua Huang

Xiao Xiao

Jinyun Chen

Affiliations

Soon will be listed here.

Abstract

Objective: To explore the feasibility of simple high-intensity focused ultrasound (HIFU) ablation for placenta increta.

Methods: Ninety-five patients after a vaginal delivery were enrolled in this retrospective cohort study, 53 patients were treated with simple HIFU ablation, and 42 patients were treated with HIFU followed by uterine curettage.

Results: All 95 patients were successfully treated with a single-session HIFU procedure, and in the control group, the necrotic placental tissue was removed with curettage. Vaginal hemorrhage did not occur in either group. The duration of bloody lochia was 25.9 ± 8.6 days in the sHIFU group and 24.2 ± 8.8 days in the control group ( > 0.05). The median serum human chorionic gonadotropin (HCG) level was 3,222 mIU/mL and 2,838 mIU/mL in the sHIFU and control groups, respectively, which decreased and returned to normal within 30 days, and the differences were not significantly on comparing the blood HCG level in the two groups at 7, 15, and 30 days after HIFU (all > 0.05). Decreased menstrual volume occurred in 85.71% of patients in the control group, which was higher than that in the sHIFU group (23.08%) (χ = 6.839, < 0.001). During 2-8 years of follow-up, six pregnancies occurred in the sHIFU group without any recurrence of placenta increta, three pregnancies occurred in the control group, and one patient developed a repeat placenta increta.

Conclusion: Simple HIFU treatment is safe and effective for postpartum placenta increta and leaving the placenta . It is a promising option for patients who wish to preserve their fertility and conceive.

Citing Articles

Placenta Accreta Spectrum: An Overview.

Ghosh A, Lee S, Lim C, Vogelzang R, Chrisman H Semin Intervent Radiol. 2023; 40(5):467-471.

PMID: 37927512 PMC: 10622243. DOI: 10.1055/s-0043-1772815.

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