Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome-A Review

Overview

Journal Nutrients

Date 2022 Apr 23

PMID 35458211

Authors

Szabolcs Varbiro

Istvan Takacs

Laszlo Tuu

Katalin Nas

Reka Eszter Sziva

Judit Reka Hetthessy

Marianna Torok

Affiliations

Soon will be listed here.

Abstract

Polycystic ovary syndrome (PCOS) is one of the most common endocrine reproductive disorders in women. Vitamin D deficiency is also quite common in this condition. The degree of vitamin D deficiency correlates with the severity of PCOS. Both male and female vitamin D levels play a role in fertility and affect the outcomes of in vitro fertilization (IVF). Moreover, fertility and IVF indicators are improved by vitamin D not only in healthy women but in those diagnosed with PCOS. Both vitamin D deficiency and PCOS increase pregnancy-related complications. Vitamin D supplementation and optimal vitamin D levels decrease both maternal and fetal risk for complications and adverse events. Furthermore, vitamin D supplementation may ameliorate or even prevent pregnancy-related reversible bone loss in mothers. This review emphasizes the roles of vitamin D deficiency and vitamin D supplementation and their correlation with PCOS regarding reproductive health.

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