Inositols, Probiotics, and Gestational Diabetes: Clinical and Epigenetic Aspects

Overview

Journal Nutrients

Date 2022 Apr 23

PMID 35458105

Authors

Ester Vitacolonna

Maria Masulli

Luisa Palmisano

Liborio Stuppia

Marica Franzago

Affiliations

Soon will be listed here.

Abstract

There is growing interest in the potential role of different stereoisomers of inositol or their combination as well as probiotics supplementation in healthy glucose metabolism during pregnancy and in promoting offspring health. The aim of this review is to clarify the effects of several inositol and probiotics-based supplements in the prevention and treatment of gestational diabetes (GDM). Moreover, we will discuss the epigenetic aspects and their short- and long-term effects in response to probiotic intervention as well as the possible implications of these findings in guiding appropriate supplementation regimens in pregnancy.

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