MR Imaging of Pediatric Brain Tumors

Overview

Journal Diagnostics (Basel)

Specialty Radiology

Date 2022 Apr 23

PMID 35454009

Authors

Alok Jaju

Kristen W Yeom

Maura E Ryan

Affiliations

Soon will be listed here.

Abstract

Primary brain tumors are the most common solid neoplasms in children and a leading cause of mortality in this population. MRI plays a central role in the diagnosis, characterization, treatment planning, and disease surveillance of intracranial tumors. The purpose of this review is to provide an overview of imaging methodology, including conventional and advanced MRI techniques, and illustrate the MRI appearances of common pediatric brain tumors.

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References

Yan J, Liu L, Wang W, Zhao Y, Li K, Li K . Radiomic Features From Multi-Parameter MRI Combined With Clinical Parameters Predict Molecular Subgroups in Patients With Medulloblastoma. Front Oncol. 2020; 10:558162. PMC: 7566191. DOI: 10.3389/fonc.2020.558162. View

Maloney E, Stanescu A, Perez F, Iyer R, Otto R, Leary S . Surveillance magnetic resonance imaging for isolated optic pathway gliomas: is gadolinium necessary?. Pediatr Radiol. 2018; 48(10):1472-1484. DOI: 10.1007/s00247-018-4154-4. View

Fernandez C, Girard N, Paz Paredes A, Bouvier-Labit C, Lena G, Figarella-Branger D . The usefulness of MR imaging in the diagnosis of dysembryoplastic neuroepithelial tumor in children: a study of 14 cases. AJNR Am J Neuroradiol. 2003; 24(5):829-34. PMC: 7975770. View

Panigrahy A, Krieger M, Gonzalez-Gomez I, Liu X, McComb J, Finlay J . Quantitative short echo time 1H-MR spectroscopy of untreated pediatric brain tumors: preoperative diagnosis and characterization. AJNR Am J Neuroradiol. 2006; 27(3):560-72. PMC: 7976960. View

Moore W, Mathis D, Gargan L, Bowers D, Klesse L, Margraf L . Pleomorphic xanthoastrocytoma of childhood: MR imaging and diffusion MR imaging features. AJNR Am J Neuroradiol. 2014; 35(11):2192-6. PMC: 7965178. DOI: 10.3174/ajnr.A4011. View

Pierce T, Provenzale J . Evaluation of apparent diffusion coefficient thresholds for diagnosis of medulloblastoma using diffusion-weighted imaging. Neuroradiol J. 2014; 27(1):63-74. PMC: 4202848. DOI: 10.15274/NRJ-2014-10007. View

Buch K, Caruso P, Ebb D, Rincon S . Balanced Steady-State Free Precession Sequence (CISS/FIESTA/3D Driven Equilibrium Radiofrequency Reset Pulse) Increases the Diagnostic Yield for Spinal Drop Metastases in Children with Brain Tumors. AJNR Am J Neuroradiol. 2018; 39(7):1355-1361. PMC: 7655452. DOI: 10.3174/ajnr.A5645. View

Villanueva K, Rea N, Krieger M . Novel Surgical and Radiologic Risk Factors for Progression or Recurrence of Pediatric Pilocytic Astrocytoma. Pediatr Neurosurg. 2019; 54(6):375-385. DOI: 10.1159/000503110. View

Ostrom Q, de Blank P, Kruchko C, Petersen C, Liao P, Finlay J . Alex's Lemonade Stand Foundation Infant and Childhood Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011. Neuro Oncol. 2014; 16 Suppl 10:x1-x36. PMC: 4277295. DOI: 10.1093/neuonc/nou327. View

10.

Hayes L, Jones R, Palasis S, Aguilera D, Porter D . Drop metastases to the pediatric spine revealed with diffusion-weighted MR imaging. Pediatr Radiol. 2011; 42(8):1009-13. DOI: 10.1007/s00247-011-2295-9. View

11.

Shaw D, Weinberger E, Brewer D, Geyer J, Berger M, Blaser S . Spinal subdural enhancement after suboccipital craniectomy. AJNR Am J Neuroradiol. 1996; 17(7):1373-7. PMC: 8338516. View

12.

Brandao L, Poussaint T . Posterior Fossa Tumors. Neuroimaging Clin N Am. 2016; 27(1):1-37. DOI: 10.1016/j.nic.2016.08.001. View

13.

Lin H, Leng X, Qin C, Du Y, Wang W, Qiu S . Choroid plexus tumours on MRI: similarities and distinctions in different grades. Cancer Imaging. 2019; 19(1):17. PMC: 6427869. DOI: 10.1186/s40644-019-0200-1. View

14.

Koeller K, Rushing E . From the archives of the AFIP: pilocytic astrocytoma: radiologic-pathologic correlation. Radiographics. 2004; 24(6):1693-708. DOI: 10.1148/rg.246045146. View

15.

Lescher S, Schniewindt S, Jurcoane A, Senft C, Hattingen E . Time window for postoperative reactive enhancement after resection of brain tumors: less than 72 hours. Neurosurg Focus. 2014; 37(6):E3. DOI: 10.3171/2014.9.FOCUS14479. View

16.

Plaza M, Borja M, Altman N, Saigal G . Conventional and advanced MRI features of pediatric intracranial tumors: posterior fossa and suprasellar tumors. AJR Am J Roentgenol. 2013; 200(5):1115-24. DOI: 10.2214/AJR.12.9725. View

17.

Sturm D, Orr B, Toprak U, Hovestadt V, Jones D, Capper D . New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. Cell. 2016; 164(5):1060-1072. PMC: 5139621. DOI: 10.1016/j.cell.2016.01.015. View

18.

Dumrongpisutikul N, Intrapiromkul J, Yousem D . Distinguishing between germinomas and pineal cell tumors on MR imaging. AJNR Am J Neuroradiol. 2011; 33(3):550-5. PMC: 7966430. DOI: 10.3174/ajnr.A2806. View

19.

Tamrazi B, Nelson M, Bluml S . Pineal Region Masses in Pediatric Patients. Neuroimaging Clin N Am. 2016; 27(1):85-97. DOI: 10.1016/j.nic.2016.08.002. View

20.

Manias K, Harris L, Davies N, Natarajan K, MacPherson L, Foster K . Prospective multicentre evaluation and refinement of an analysis tool for magnetic resonance spectroscopy of childhood cerebellar tumours. Pediatr Radiol. 2018; 48(11):1630-1641. PMC: 6153873. DOI: 10.1007/s00247-018-4182-0. View