Brown Adipose Tissue Thermogenesis Among a Small Sample of Reindeer Herders from Sub-Arctic Finland

Overview

Journal J Physiol Anthropol

Publisher Biomed Central

Specialty Social Sciences

Date 2022 Apr 21

PMID 35443705

Authors

Cara Ocobock

Paivi Soppela

Minna Turunen

Ville Stenback

Karl-Heinz Herzig

Affiliations

Soon will be listed here.

Abstract

Introduction: Interest in human physiological responses to cold stress have seen a resurgence in recent years with a focus on brown adipose tissue (BAT), a mitochondria dense fat specialized for heat production. However, a majority of the work examining BAT has been conducted among temperate climate populations.

Methods: To expand our understanding of BAT thermogenesis in a cold climate population, we measured, using indirect calorimetry and thermal imaging, metabolic rate and body surface temperatures of BAT-positive and BAT-negative regions at room temperature, and mild cold exposure of resting participants from a small sample of reindeer herders (N = 22, 6 females) from sub-Arctic Finland.

Results: We found that most herders experienced a significant mean 8.7% increase in metabolic rates, preferentially metabolized fatty acids, and maintained relatively warmer body surface temperatures at the supraclavicular region (known BAT location) compared to the sternum, which has no associated BAT. These results indicate that the herders in this sample exhibit active BAT thermogenesis in response to mild cold exposure.

Conclusions: This study adds to the rapidly growing body of work looking at the physiological and thermoregulatory significance of BAT and the important role it may play among cold stressed populations.

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