Safety and Efficacy of 27-gauge Transconjunctival Vitrectomy for the Diagnosis of Posterior Uveitis or Pan Uveitis of Unknown Origin

Overview

Journal BMC Ophthalmol

Publisher Biomed Central

Specialty Ophthalmology

Date 2022 Apr 20

PMID 35439966

Authors

Atsushi Sakai

Mizuki Tagami

Norihiko Misawa

Manabu Yamamoto

Takeya Kohno

Shigeru Honda

Affiliations

Soon will be listed here.

Abstract

Background: Diagnostic vitrectomy is an important method for evaluating uveitis, and its diagnostic utility is high regardless of whether the uveitis is infectious or non-infectious. The course of diagnostic vitreous surgery with 27-gauge pars plana vitrectomy and perioperative complications is reported.

Methods: An observational retrospective study of patients who underwent 27-gauge diagnostic vitrectomy due to atypical intraocular inflammation was conducted. The final diagnosis rate, complications due to surgery, preoperative visual acuity, and postoperative visual acuity (1 month and 6 months after surgery) were examined retrospectively.

Results: Diagnostic vitreous surgery was performed in 32 patients and 35 eyes (14 males and 18 females, age 14-85 years, median 67 years) during the study period. The average operation time was 52 min for 19 eyes with cataract surgery and 35 min for 16 eyes without cataract surgery. Preoperative log(minimum angle of resolution [MAR]) visual acuity was 0.84 ± 0.87, 1-month postoperative logMAR visual acuity was 0.41 ± 0.55 (p = 0.004, n = 28), and 6-month postoperative average logMAR visual acuity was 0.45 ± 0.73 (p = 0.012, n = 15). The diagnosis was made by diagnostic vitrectomy in 19 cases (54%). Postoperative complications were observed in 2 of 35 postoperative patients (5%); one involved increased intraocular pressure, and the other case involved vitreous hemorrhage of the eye, necessitating reoperation.

Conclusion: Diagnostic 27-gauge vitrectomy could be effective for evaluating intraocular inflammation.

Citing Articles

Relationship between vitreous interleukin-6 levels and vitreous particles findings on widefield optical coherence tomography in posterior uveitis.

Tomita M, Tagami M, Misawa N, Sakai A, Haruna Y, Honda S PLoS One. 2024; 19(1):e0297201.

PMID: 38232093 PMC: 10793905. DOI: 10.1371/journal.pone.0297201.

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