DMSO-allyl Bromide: a Mild and Efficient Reagent for Atom Economic One-pot -allylation and Bromination of 2°-aryl Amines, 2-aryl Aminoamides, Indoles and 7-aza Indoles

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2022 Apr 15

PMID 35425207

Authors

Suresh Snoxma Smile

Motakatla Novanna

Sathananthan Kannadasan

Ponnusamy Shanmugam

Affiliations

Soon will be listed here.

Abstract

A mixture DMSO-allyl bromide has been developed as a reagent for an atom economic one-pot -allylation and aryl bromination under basic conditions. Utilizing this reagent, -allylation-bromination of a number of 2°-aryl amines, aryl aminoamides, indoles, and 7-aza indoles has been achieved. The scope of the substrates and limitations, the synthetic utility of the products, and a plausible reaction mechanism have been proposed.

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