Dual C-H Activation: Rh(iii)-catalyzed Cascade π-extended Annulation of 2-arylindole with Benzoquinone

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2022 Apr 15

PMID 35423833

Authors

Qijing Zhang

Qianrong Li

Chengming Wang

Affiliations

Soon will be listed here.

Abstract

A rhodium-catalyzed, N-H free indole directed cyclization reaction of benzoquinone a dual C-H activation strategy is disclosed. This protocol has a good functional group tolerance and affords useful indole-fused heterocylces. Besides, it is insensitive to moisture, commercially available solvent can be directly used and work quite well for this transformation.

Citing Articles

Rh(iii)-catalyzed regioselective C-H activation dialkenylation/annulation cascade for rapid access to 6-isoindolo[2,1-]indole.

Zhang F, Zhu X, Luo B, Wang C RSC Adv. 2022; 11(41):25194-25198.

PMID: 35478900 PMC: 9037025. DOI: 10.1039/d1ra02998c.

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