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Acute Kidney Injury During Pregnancy in Kidney Transplant Recipients

Overview
Journal Clin Transplant
Specialty General Surgery
Date 2022 Apr 9
PMID 35396888
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Abstract

Pregnancy-related acute kidney injury (AKI) is a public health problem and remains an important cause of maternal and fetal morbidity and mortality. The incidence of pregnancy-related AKI has increased in developed countries due to increase in maternal age and higher detection rates. Pregnancy in women with kidney transplants is associated with higher adverse outcomes like preeclampsia, preterm births, and allograft dysfunction, but limited data exists on causes and outcomes of pregnancy-related AKI in the kidney transplant population. Diagnosis of AKI during pregnancy remains challenging in kidney transplant recipients due to lack of diagnostic criteria. Management of pregnancy-related AKI in the kidney transplant population requires a multidisciplinary team consisting of transplant nephrologists, high-risk obstetricians, and neonatologists. In this review, we discuss pregnancy-related AKI in women with kidney transplants, etiologies, pregnancy outcomes, and management strategies.

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References
1.
Murray J, Reid D, Harrison J, MERRILL J . Successful pregnancies after human renal transplantation. N Engl J Med. 1963; 269:341-3. DOI: 10.1056/NEJM196308152690704. View

2.
Shah S, Venkatesan R, Gupta A, Sanghavi M, Welge J, Johansen R . Pregnancy outcomes in women with kidney transplant: Metaanalysis and systematic review. BMC Nephrol. 2019; 20(1):24. PMC: 6345071. DOI: 10.1186/s12882-019-1213-5. View

3.
Kattah A, Albadri S, Alexander M, Smith B, Parashuram S, Mai M . Impact of Pregnancy on GFR Decline and Kidney Histology in Kidney Transplant Recipients. Kidney Int Rep. 2022; 7(1):28-35. PMC: 8720805. DOI: 10.1016/j.ekir.2021.10.010. View

4.
Chewcharat A, Kattah A, Thongprayoon C, Cheungpasitporn W, Boonpheng B, Gonzalez Suarez M . Comparison of hospitalization outcomes for delivery and resource utilization between pregnant women with kidney transplants and chronic kidney disease in the United States. Nephrology (Carlton). 2021; 26(11):879-889. DOI: 10.1111/nep.13938. View

5.
Hebert M, Zheng S, Hays K, Shen D, Davis C, Umans J . Interpreting tacrolimus concentrations during pregnancy and postpartum. Transplantation. 2013; 95(7):908-15. PMC: 3637974. DOI: 10.1097/TP.0b013e318278d367. View