Synenkephalin in Bovine and Human Spinal Cord

Overview

Journal Cell Tissue Res

Specialties Anatomy & Histology
Cell Biology

Date 1986 Jan 1

PMID 3539355

Authors

J Schoenen

F Lotstra

D Liston

J Rossier

J J Vanderhaeghen

Affiliations

Soon will be listed here.

Abstract

Synenkephalin, which comprises 70 residues at the aminoterminal of proenkephalin, was studied with immunocytochemical methods in the human and bovine spinal cord. Immunoreactive fibers had the same general distribution as methionine-enkephalin, but not as leucine-enkephalin fibers. They were found in all spinal layers and were most numerous in lamina II (outer zone) and V-VI (lateral portion). Synenkephalin immunoreactivity was overall less dense than that of the enkephalins. These results suggest that proenkephalin is the precursor protein also in enkephalinergic neurons of the human spinal cord.

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