What Can We Learn from Synaptic Connectivity Maps About Cerebellar Internal Models?

Overview

Journal Cerebellum

Publisher Springer

Specialty Neurology

Date 2022 Apr 8

PMID 35391650

Authors

Ludovic Spaeth

Philippe Isope

Affiliations

Soon will be listed here.

Abstract

The cerebellum is classically associated with fine motor control, motor learning, and timing of actions. However, while its anatomy is well described and many synaptic plasticity have been identified, the computation performed by the cerebellar cortex is still debated. We, here, review recent advances on how the description of the functional synaptic connectivity between granule cells and Purkinje cells support the hypothesis that the cerebellum stores internal models of the body coordinates. We propose that internal models are specific of the task and of the locomotor context of each individual.

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