» Articles » PMID: 35371803

Chondroblastoma of the Occipital Bone With Atypical Genetic Markers: A Case Report

Overview
Journal Cureus
Date 2022 Apr 4
PMID 35371803
Authors
Affiliations
Soon will be listed here.
Abstract

Chondroblastoma is a rare bone tumor, most often found in epiphyseal plates of long bones. It has infrequently been reported in the skull, most often in the temporal bone. We present a case of chondroblastoma of the occipital bone in a pediatric patient presenting with a bony protuberance of the occiput and imaging consistent with obstructive hydrocephalus, which persisted even after removal of the obstructing tumor. Pathological examination demonstrated that this unusually placed tumor also lacked the classic genetic markers typically associated with chondroblastoma.

Citing Articles

Chondroblastoma of the occipital bone with aneurysmal bone cyst: A rare case report.

Bi D, Wang Z, Dai Z, Yang S, Zeng G, Wang L Childs Nerv Syst. 2024; 40(12):4323-4327.

PMID: 39503746 DOI: 10.1007/s00381-024-06632-0.

References
1.
Araujo J, de Castro G, Iafigliola M, BALBO R . [Benign chondroblastoma of the occipital bone. A case report]. Arq Neuropsiquiatr. 1995; 53(4):834-6. DOI: 10.1590/s0004-282x1995000500023. View

2.
Venneker S, Szuhai K, Hogendoorn P, Bovee J . Mutation-driven epigenetic alterations as a defining hallmark of central cartilaginous tumours, giant cell tumour of bone and chondroblastoma. Virchows Arch. 2019; 476(1):135-146. PMC: 6968983. DOI: 10.1007/s00428-019-02699-2. View

3.
Kutz Jr J, Verma S, Tan H, Lo W, Slattery 3rd W, Friedman R . Surgical management of skull base chondroblastoma. Laryngoscope. 2007; 117(5):848-53. DOI: 10.1097/MLG.0b013e3180337da6. View

4.
Turcotte R, Kurt A, Sim F, Unni K, Mcleod R . Chondroblastoma. Hum Pathol. 1993; 24(9):944-9. DOI: 10.1016/0046-8177(93)90107-r. View

5.
Ohnishi T, Oku Y, Yamamoto K, Morimura Y, Ushio Y . Benign chondroblastoma of the occipital bone. Surg Neurol. 1985; 24(1):52-6. DOI: 10.1016/0090-3019(85)90064-3. View