MicroED: Conception, Practice and Future Opportunities

Overview

Journal IUCrJ

Date 2022 Apr 4

PMID 35371502

Authors

Max T B Clabbers

Anna Shiriaeva

Tamir Gonen

Affiliations

Soon will be listed here.

Abstract

This article documents a keynote seminar presented at the IUCr Congress in Prague, 2021. The cryo-EM method microcrystal electron diffraction is described and put in the context of macromolecular electron crystallography from its origins in 2D crystals of membrane proteins to today's application to 3D crystals a millionth the size of that needed for X-ray crystallography. Milestones in method development and applications are described with an outlook to the future.

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