Acute Disseminated Encephalitis (ADEM) As the First Presentation of COVID-19; a Case Report
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Introduction: and importance: Neurological ailments are reported during and after SARS-COV-2 infection.
Case Presentation: We report a 67-year-old Iranian man with COVID-19 infection and Acute Disseminated Encephalomyelitis (ADEM) whose neurological symptoms appeared before clinical and radiological pulmonary manifestations.
Clinical Discussion: COVID-19 can cause neurological complication without entering the CNS via para infectious inflammatory mechanisms.
Conclusions: This report shows that ADEM might be among primary presentations of COVID-19.
Stoian A, Bajko Z, Stoian M, Cioflinc R, Niculescu R, Arbanasi E Vaccines (Basel). 2023; 11(7).
PMID: 37515041 PMC: 10385010. DOI: 10.3390/vaccines11071225.
Tabatabaee S, Rezania F, Soleimani S, Mirzaasgari Z Clin Case Rep. 2022; 10(12):e6716.
PMID: 36523374 PMC: 9748218. DOI: 10.1002/ccr3.6716.
Encephalitis in Patients with COVID-19: A Systematic Evidence-Based Analysis.
Islam M, Cavestro C, Alam S, Kundu S, Kamal M, Reza F Cells. 2022; 11(16).
PMID: 36010650 PMC: 9406394. DOI: 10.3390/cells11162575.
Status epilepticus and the presence of SARS-COV-2 in the cerebrospinal fluid: A case report.
Abdolahi S, Ashayeri Ahmadabad R, Gorji A, Mirzaasgari Z Clin Case Rep. 2022; 10(8):e6214.
PMID: 35957773 PMC: 9361715. DOI: 10.1002/ccr3.6214.
The diagnosis of SARS-CoV-2 associated ADEM requires the exclusion of all differential diagnoses.
Finsterer J, Scorza F Ann Med Surg (Lond). 2022; 77:103662.
PMID: 35493414 PMC: 9033291. DOI: 10.1016/j.amsu.2022.103662.