Can Pulmonary RNA Delivery Improve Our Pandemic Preparedness?

Overview

Journal J Control Release

Specialty Pharmacology

Date 2022 Mar 31

PMID 35358609

Authors

Olivia M Merkel

Affiliations

Soon will be listed here.

Abstract

The coronavirus pandemic has changed our perception of RNA medicines, and RNA vaccines have revolutionized our pandemic preparedness. But are we indeed prepared for the next variant or the next emerging virus? How can we prepare? And what does the role of inhaled antiviral RNA play in this regard? When the pandemic started, I rerouted much of the ongoing inhaled RNA delivery research in my group towards the inhibition and treatment of respiratory viral infections. Two years later, I have taken the literature, past and ongoing clinical trials into consideration and have gained new insights based on our collaborative research which I will discuss in this oration.

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