Empirically Derived Dietary Pattern and Odds of Non-alcoholic Fatty Liver Diseases in Overweight and Obese Adults: a Case-control Study

Overview

Journal BMC Gastroenterol

Publisher Biomed Central

Specialty Gastroenterology

Date 2022 Mar 31

PMID 35354433

Authors

Nasir Talenezhad

Farhang Mirzavandi

Shahab Rahimpour

Amir Pasha Amel Shahbaz

Mohammad Mohammadi

Mahdieh Hosseinzadeh

Affiliations

Soon will be listed here.

Abstract

Background: The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising at an exponential rate throughout the world. Given the confirmed association between nutritional status and NAFLD, this study aimed to investigate the relationship of dietary patterns with NAFLD in overweight and obese adults.

Methods: In this age- and gender-matched case-control study, 115 newly diagnosed cases and 102 control individuals participated. A validated 178-item semi-quantitative food frequency questionnaire was administered to assess the participants' dietary data. Dietary patterns were extracted from 24 predefined food groups by factor analysis. Multivariate logistic regression was run to evaluate the relationship between dietary patterns and NAFLD.

Results: Factor analysis resulted in: "western", "traditional", and "snack and sweets" dietary patterns. The NAFLD odds were greater in participants at the highest quintile of the "western" dietary pattern than the lowest quintile (OR: 3.52; 95% CI: 1.64, 8.61). A significant increasing trend was observed in NAFLD odds across increasing quintiles of the "western" dietary pattern (P-trend = 0.01). After adjusting for the potential confounders, this relationship remained significant (OR: 3.30; 95% CI: 1.06-10.27). After full adjustments, NAFLD had no association with "traditional" or "snack and sweets" dietary patterns.

Conclusion: The "western" dietary pattern containing fast food, refined grains, liquid oil, pickles, high-fat dairy, sweet desserts, red meat, tea, and coffee was associated with increased odds of NAFLD. However, further prospective studies are required to establish these results.

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References

Hekmatdoost A, Shamsipour A, Meibodi M, Gheibizadeh N, Eslamparast T, Poustchi H . Adherence to the Dietary Approaches to Stop Hypertension (DASH) and risk of Nonalcoholic Fatty Liver Disease. Int J Food Sci Nutr. 2016; 67(8):1024-9. DOI: 10.1080/09637486.2016.1210101. View

Hosseini Esfahani F, Asghari G, Mirmiran P, Azizi F . Reproducibility and relative validity of food group intake in a food frequency questionnaire developed for the Tehran Lipid and Glucose Study. J Epidemiol. 2010; 20(2):150-8. PMC: 3900814. DOI: 10.2188/jea.je20090083. View

Fakhoury-Sayegh N, Younes H, Heraoui G, Sayegh R . Nutritional Profile and Dietary Patterns of Lebanese Non-Alcoholic Fatty Liver Disease Patients: A Case-Control Study. Nutrients. 2017; 9(11). PMC: 5707717. DOI: 10.3390/nu9111245. View

Schulze M, Manson J, Ludwig D, Colditz G, Stampfer M, Willett W . Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA. 2004; 292(8):927-34. DOI: 10.1001/jama.292.8.927. View

McCarthy E, Rinella M . The role of diet and nutrient composition in nonalcoholic Fatty liver disease. J Acad Nutr Diet. 2012; 112(3):401-9. DOI: 10.1016/j.jada.2011.10.007. View

Esmaillzadeh A, Azadbakht L . Major dietary patterns in relation to general obesity and central adiposity among Iranian women. J Nutr. 2008; 138(2):358-63. DOI: 10.1093/jn/138.2.358. View

Yuan Y, Li F, Meng P, You J, Wu M, Li S . Gender Difference on the Association between Dietary Patterns and Obesity in Chinese Middle-Aged and Elderly Populations. Nutrients. 2016; 8(8). PMC: 4997363. DOI: 10.3390/nu8080448. View

Yu J, Marsh S, Hu J, Feng W, Wu C . The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background. Gastroenterol Res Pract. 2016; 2016:2862173. PMC: 4876215. DOI: 10.1155/2016/2862173. View

Han J, Jo A, Lee S, Bae H, Won Jun D, Cho Y . Associations between intakes of individual nutrients or whole food groups and non-alcoholic fatty liver disease among Korean adults. J Gastroenterol Hepatol. 2014; 29(6):1265-72. DOI: 10.1111/jgh.12520. View

10.

Yang C, Shu L, Wang S, Wang J, Zhou Y, Xuan Y . Dietary Patterns Modulate the Risk of Non-Alcoholic Fatty Liver Disease in Chinese Adults. Nutrients. 2015; 7(6):4778-91. PMC: 4488813. DOI: 10.3390/nu7064778. View

11.

Chan R, Wong V, Chu W, Wong G, Li L, Leung J . Diet-Quality Scores and Prevalence of Nonalcoholic Fatty Liver Disease: A Population Study Using Proton-Magnetic Resonance Spectroscopy. PLoS One. 2015; 10(9):e0139310. PMC: 4587971. DOI: 10.1371/journal.pone.0139310. View

12.

Hamaguchi M, Kojima T, Takeda N, Nagata C, Takeda J, Sarui H . Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease. World J Gastroenterol. 2007; 13(10):1579-84. PMC: 4146902. DOI: 10.3748/wjg.v13.i10.1579. View

13.

Petit J, Guiu B, Duvillard L, Jooste V, Brindisi M, Athias A . Increased erythrocytes n-3 and n-6 polyunsaturated fatty acids is significantly associated with a lower prevalence of steatosis in patients with type 2 diabetes. Clin Nutr. 2012; 31(4):520-5. DOI: 10.1016/j.clnu.2011.12.007. View

14.

Jia Q, Xia Y, Zhang Q, Wu H, Du H, Liu L . Dietary patterns are associated with prevalence of fatty liver disease in adults. Eur J Clin Nutr. 2015; 69(8):914-21. DOI: 10.1038/ejcn.2014.297. View

15.

Younossi Z, Koenig A, Abdelatif D, Fazel Y, Henry L, Wymer M . Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2015; 64(1):73-84. DOI: 10.1002/hep.28431. View

16.

Oddy W, Herbison C, Jacoby P, Ambrosini G, OSullivan T, Ayonrinde O . The Western dietary pattern is prospectively associated with nonalcoholic fatty liver disease in adolescence. Am J Gastroenterol. 2013; 108(5):778-85. DOI: 10.1038/ajg.2013.95. View

17.

Fan J, Kim S, Wong V . New trends on obesity and NAFLD in Asia. J Hepatol. 2017; 67(4):862-873. DOI: 10.1016/j.jhep.2017.06.003. View

18.

Tetri L, Basaranoglu M, Brunt E, Yerian L, Neuschwander-Tetri B . Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent. Am J Physiol Gastrointest Liver Physiol. 2008; 295(5):G987-95. PMC: 4059366. DOI: 10.1152/ajpgi.90272.2008. View

19.

Younossi Z, Anstee Q, Marietti M, Hardy T, Henry L, Eslam M . Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention. Nat Rev Gastroenterol Hepatol. 2017; 15(1):11-20. DOI: 10.1038/nrgastro.2017.109. View

20.

Adriano L, Sampaio H, Arruda S, Portela C, Melo M, Carioca A . Healthy dietary pattern is inversely associated with non-alcoholic fatty liver disease in elderly. Br J Nutr. 2016; 115(12):2189-95. DOI: 10.1017/S0007114516001410. View