Omega-3 Fatty Acids Coordinate Glucose and Lipid Metabolism in Diabetic Patients

Overview

Journal Lipids Health Dis

Publisher Biomed Central

Specialties Biochemistry
Endocrinology

Date 2022 Mar 26

PMID 35337345

Authors

Pasquale Mone

Fahimeh Varzideh

Urna Kansakar

Carmine Infante

Angela Lombardi

Antonio de Donato

Salvatore Frullone

Gaetano Santulli

Affiliations

Soon will be listed here.

Abstract

Omega 3 polyunsaturated fatty acids (n-3 PUFA) are known to have beneficial effects on cardiovascular and metabolic health. However, whether different sources of n-3 PUFA, for instance fatty fish vs vegetable oils, could elicit different effects on glucose and lipid metabolism, remains to be determined. Herein we examine recent findings showing that while a plant-based n-3 PUFA supplementation for six months can reduce fasting blood glucose, marine-based n-3 PUFA can instead reduce serum levels of triglycerides. We also discuss the potential molecular mechanisms that could underlie these different effects on the regulation of glycolipid metabolism.

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