PH and Redox Dual-Responsive Mesoporous Silica Nanoparticle As Nanovehicle for Improving Fungicidal Efficiency

Overview

Journal Materials (Basel)

Publisher MDPI

Date 2022 Mar 25

PMID 35329659

Authors

Litao Wu

Hua Pan

Weilan Huang

Zhongxuan Hu

Meijing Wang

Fang Zhang

Affiliations

Soon will be listed here.

Abstract

Prochloraz (Pro) controlled-release nanoparticles (NPs) based on bimodal mesoporous silica (BMMs) with redox and pH dual responses were successfully prepared in this study. BMMs was modified by a silane coupling agent containing a disulfide bond, and β-cyclodextrin (β-CD) was grafted on the surface of the NPs through host-guest interaction. Pro was encapsulated into the pores of nanoparticles by physical adsorption. NPs had a spherical structure, and their average diameter was 546.4 ± 3.0 nm as measured by dynamic light scattering. The loading rate of Pro was 28.3%, and it achieved excellent pH/redox dual-responsive release performance under acidic conditions. Foliage adhesion tests on tomato leaves showed that the NPs had good adhesion properties compared to the commercial formulation. Owing to the protection of the nanocarrier, NPs became more stable under ultraviolet light and high temperature, which improves the efficient utilization of Pro. Biological activity tests showed that the NPs exhibited effective antifungal activity, and the benign biosafety of the nanocarrier was also observed through toxicology tests on cell viability and the growth of (). This work provides a promising approach to improving the efficient utilization of pesticides and reducing environmental pollution.

Citing Articles

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