Cytochromes P450 of : Implication in Biological Functions and Metabolism of Xenobiotics

Overview

Journal Biomolecules

Publisher MDPI

Specialties Biochemistry
Molecular Biology

Date 2022 Mar 25

PMID 35327534

Authors

Lucie Larigot

Daniel Mansuy

Ilona Borowski

Xavier Coumoul

Julien Dairou

Affiliations

Soon will be listed here.

Abstract

is an important model used for many aspects of biological research. Its genome contains 76 genes coding for cytochromes P450 (P450s), and few data about the biochemical properties of those P450s have been published so far. However, an increasing number of articles have appeared on their involvement in the metabolism of xenobiotics and endobiotics such as fatty acid derivatives and steroids. Moreover, the implication of some P450s in various biological functions of , such as survival, dauer formation, life span, fat content, or lipid metabolism, without mention of the precise reaction catalyzed by those P450s, has been reported in several articles. This review presents the state of our knowledge about P450s.

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