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Vaccine-Associated Measles Encephalitis in Immunocompromised Child, California, USA

Overview
Journal Emerg Infect Dis
Specialty Infectious Diseases
Date 2022 Mar 23
PMID 35318930
Authors
Cristina Costales
Malaya K Sahoo
Chunhong Huang
Carolina V Guimaraes
Donald Born
Lauren Kushner
Hayley A Gans
Thuy A Doan
Benjamin A Pinsky
Affiliations
Soon will be listed here.
Abstract

We report a fatal case of vaccine-associated measles encephalitis in an immunocompromised child in California, USA. The infection was confirmed by whole-genome RNA sequencing of measles virus from brain tissue. We observed biased matrix-gene hypermutation consistent with persistent measles virus central nervous system infection.

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