Background:
Mobile health (mHealth) tools have emerged as a promising health care technology that may contribute to cost savings, better access to care, and enhanced clinical outcomes; however, it is important to ensure their acceptance and adoption to harness this potential. Patient adoption has been recognized as a key challenge that requires further exploration.
Objective:
The aim of this review was to systematically investigate the literature to understand the factors affecting patients' adoption of mHealth tools by considering sociotechnical factors (from technical, social, and health perspectives).
Methods:
A structured search was completed following the participants, intervention, comparators, and outcomes framework. We searched the MEDLINE, PubMed, Cochrane Library, and SAGE databases for studies published between January 2011 and July 2021 in the English language, yielding 5873 results, of which 147 studies met the inclusion criteria. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and the Cochrane Handbook were followed to ensure a systematic process. Extracted data were analyzed using NVivo (QSR International), with thematic analysis and narrative synthesis of emergent themes.
Results:
The technical factors affecting patients' adoption of mHealth tools were categorized into six key themes, which in turn were divided into 20 subthemes: usefulness, ease of use, data-related, monetary factors, technical issues, and user experience. Health-related factors were categorized into six key themes: the disease or health condition, the care team's role, health consciousness and literacy, health behavior, relation to other therapies, integration into patient journey, and the patients' insurance status. Social and personal factors were divided into three key clusters: demographic factors, personal characteristics, and social and cultural aspects; these were divided into 19 subthemes, highlighting the importance of considering these factors when addressing potential barriers to mHealth adoption and how to overcome them.
Conclusions:
This review builds on the growing body of research that investigates patients' adoption of mHealth services and highlights the complexity of the factors affecting adoption, including personal, social, technical, organizational, and health care aspects. We recommend a more patient-centered approach by ensuring the tools' fit into the overall patient journey and treatment plan, emphasizing inclusive design, and warranting comprehensive patient education and support. Moreover, empowering and mobilizing clinicians and care teams, addressing ethical data management issues, and focusing on health care policies may facilitate adoption.
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Acceptance of a mental health app (JoyPop) for postsecondary students: a prospective evaluation using the UTAUT2.
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Front Digit Health. 2025; 7:1503428.
PMID: 40041123
PMC: 11876143.
DOI: 10.3389/fdgth.2025.1503428.
From diabetes care to prevention: review of prediabetes apps in the DACH region.
Lim D, Meier L, Cadwell K, Jacob C
Mhealth. 2025; 11:8.
PMID: 39944857
PMC: 11811653.
DOI: 10.21037/mhealth-24-57.
Think-Aloud Testing of a Companion App for Colonoscopy Examinations: Usability Study.
Jacob C, Muller R, Schuler S, Rey A, Rey G, Armenian B
JMIR Hum Factors. 2025; 12:e67043.
PMID: 39937786
PMC: 11838146.
DOI: 10.2196/67043.
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Jacob C, Brasier N, Laurenzi E, Heuss S, Mougiakakou S, Coltekin A
J Med Internet Res. 2025; 27:e67485.
PMID: 39909417
PMC: 11840377.
DOI: 10.2196/67485.
Application of Patient-Generated Health Data Among Older Adults With Cancer: Scoping Review.
Kim Y, Kim G, Cho H, Kim Y, Choi M
J Med Internet Res. 2025; 27:e57379.
PMID: 39903506
PMC: 11836591.
DOI: 10.2196/57379.
Intention to use mobile phone-based TB screening among HIV patients in Debre Tabor Town public health facilities, Northwest Ethiopia: a cross-sectional study.
Ayalew T, Gashu K, Jemere A, Baykemagn N
BMC Public Health. 2025; 25(1):203.
PMID: 39825290
PMC: 11740710.
DOI: 10.1186/s12889-025-21381-8.
Digital health interventions in adult intensive care and recovery after critical illness to promote survivorship care.
da Silva A, Merolli M, Fini N, Granger C, Gustafson O, Parry S
J Intensive Care Soc. 2025; 26(1):96-104.
PMID: 39764433
PMC: 11700390.
DOI: 10.1177/17511437241311105.
Factors Impacting the Adoption and Potential Reimbursement of a Virtual Reality Tool for Pain Management in Switzerland: Qualitative Case Study.
Lurtz J, Sauter T, Jacob C
JMIR Hum Factors. 2024; 11:e59073.
PMID: 39631071
PMC: 11634046.
DOI: 10.2196/59073.
Sleep well, worry less: A co-design study for the development of the SMILE app.
Cormier M, Orr M, Kaser A, MacDonald H, Chorney J, Meier S
Digit Health. 2024; 10:20552076241283242.
PMID: 39398895
PMC: 11468482.
DOI: 10.1177/20552076241283242.
Health Maintenance Organization-mHealth Versus Face-to-Face Interaction for Health Care in Israel: Cross-Sectional Web-Based Survey Study.
Zigdon A, Zwilling M, Zigdon O, Reges O
J Med Internet Res. 2024; 26:e55350.
PMID: 39348674
PMC: 11474126.
DOI: 10.2196/55350.
Leveraging Personal Technologies in the Treatment of Schizophrenia Spectrum Disorders: Scoping Review.
DArcey J, Torous J, Asuncion T, Tackaberry-Giddens L, Zahid A, Ishak M
JMIR Ment Health. 2024; 11:e57150.
PMID: 39348196
PMC: 11474131.
DOI: 10.2196/57150.
Evolutionary Trends in the Adoption, Adaptation, and Abandonment of Mobile Health Technologies: Viewpoint Based on 25 Years of Research.
Portz J, Moore S, Bull S
J Med Internet Res. 2024; 26:e62790.
PMID: 39331463
PMC: 11470221.
DOI: 10.2196/62790.
Standardized assessment of evidence supporting the adoption of mobile health solutions: A Clinical Consensus Statement of the ESC Regulatory Affairs Committee: Developed in collaboration with the European Heart Rhythm Association (EHRA), the....
Caiani E, Kemps H, Hoogendoorn P, Asteggiano R, Bohm A, Borregaard B
Eur Heart J Digit Health. 2024; 5(5):509-523.
PMID: 39318699
PMC: 11417493.
DOI: 10.1093/ehjdh/ztae042.
Evaluating the Adoption of mHealth Technologies by Community Health Workers to Improve the Use of Maternal Health Services in Sub-Saharan Africa: Systematic Review.
Kachimanga C, Zaniku H, Divala T, Ket J, Mukherjee J, Palazuelos D
JMIR Mhealth Uhealth. 2024; 12:e55819.
PMID: 39316427
PMC: 11462100.
DOI: 10.2196/55819.
A clinical decision support tool for metabolic dysfunction-associated steatohepatitis in real-world clinical settings: a mixed-method implementation research study protocol.
Fishman J, Alexander T, Kim Y, Kindt I, Mendez P
J Comp Eff Res. 2024; 13(10):e240085.
PMID: 39301878
PMC: 11426282.
DOI: 10.57264/cer-2024-0085.
Digital health as a tool for patient activation and improving quality of care for heart failure.
Verma A, Azizi Z, Sandhu A
Heart Fail Rev. 2024; 29(6):1239-1245.
PMID: 39240405
DOI: 10.1007/s10741-024-10433-7.
Consumer Perspectives for a Future Mobile App to Document Real-World Listening Difficulties: Qualitative Study.
Galvin K, Tomlin D, Timmer B, McNeice Z, Mount N, Gray K
JMIR Form Res. 2024; 8:e47578.
PMID: 39042452
PMC: 11303898.
DOI: 10.2196/47578.
Applying the Unified Theory of Acceptance and Use of Technology to Identify Factors Associated With Intention to Use Teledelivered Supportive Care Among Recently Diagnosed Breast Cancer Survivors During COVID-19 in Hong Kong: Cross-Sectional Survey.
Yeung N, Lau S, Mak W, Cheng C, Chan E, Siu J
JMIR Cancer. 2024; 10:e51072.
PMID: 38935942
PMC: 11240077.
DOI: 10.2196/51072.
Assessing Telemedicine Demand and Viability in Indonesian Geriatric Clinics: A Comprehensive HOT FIT and Sociotechnical Analysis.
Kemala Sari D, Lipoeto N, Bachtiar H, Catri I, Sari N, Semiarty R
Curr Aging Sci. 2024; .
PMID: 38920080
PMC: 11851141.
DOI: 10.2174/0118746098302999240522092726.
Experiences of community health workers on adopting mHealth in rural Malawi: A qualitative study.
Kachimanga C, Mulwafu M, Ndambo M, Harare J, Murkherjee J, Kulinkina A
Digit Health. 2024; 10:20552076241253994.
PMID: 38757088
PMC: 11097726.
DOI: 10.1177/20552076241253994.