Using Seasonality and Birdsong to Understand Mechanisms Underlying Context-appropriate Shifts in Social Motivation and Reward

Social motivation and reward are dynamic and flexible, shifting adaptively across contexts to meet changing social demands. This is exceptionally apparent when seasonal contexts are considered in seasonally breeding songbirds as they cycle from periods of sexual motivation and reward during the breeding season to periods of extreme gregariousness outside the breeding season when non-sexual social interactions gain reward value, motivating birds to form flocks. Here we review evidence demonstrating a key integrative role for the medial preoptic area (mPOA) in the seasonally-appropriate adjustment of behaviors, with seasonal changes in dopamine activity in mPOA adjusting social motivation and changes in opioid activity modifying social reward. Experiments demonstrate that dramatic seasonal fluctuations in steroid hormone concentrations alter patterns of opioid- and dopamine-related protein and gene expression in mPOA to modify social motivation and reward to meet seasonal changes in social demands. These studies of birdsong and seasonality provide new insights into neural and endocrine mechanisms underlying adaptive changes in social motivation and reward and highlight an underappreciated, evolutionarily conserved role for the mPOA in important social behaviors in non-reproductive contexts.