Functional Outcomes of Cancer Patients in an Acute Inpatient Setting at King Fahad Medical City

Overview

Journal J Phys Ther Sci

Date 2022 Mar 16

PMID 35291471

Authors

Amani A AlJohi

Safanah AlSaeed

Affiliations

Soon will be listed here.

Abstract

[Purpose] Cancer survivors have functional impairments that adversely affect patients' quality of life (QoL). Acute rehabilitation helps to reduce disability and improves QoL in cancer survivors. This study investigated the potential improvement in mobility levels and QoL of cancer patients during acute inpatient physical therapy (PT) from admission to discharge. [Participants and Methods] This was a cross-sectional study conducted at King Fahad Medical City, Riyadh. Acute inpatient cancer survivors (n=99) were assessed at their admission and discharge. The primary outcome measure was the AM-PAC "6-Clicks" Basic Mobility, Functional Assessment of Cancer Therapy-General (FACT-G7) and the Karnofsky Performance Scale (KPS). [Results] Overall, 82.8% of cancer patients were discharged home. There were significant improvements in all the three outcome measures for all the patients from admission to discharge. Patients who were discharged home exhibited significantly better improvement in all the scales. Factors that predicted discharge mobility and quality of life were discharge destination, number of PT sessions, and baseline admission scores. [Conclusion] The study found that acute inpatient cancer rehabilitation helps to improve mobility and QoL. Rehabilitation programs available in Saudi Arabia are limited, and it is important to integrate the cancer rehabilitation model into the oncology services.

References

Kus S, Muller M, Strobl R, Grill E . Patient goals in post-acute geriatric rehabilitation--goal attainment is an indicator for improved functioning. J Rehabil Med. 2011; 43(2):156-61. DOI: 10.2340/16501977-0636. View

Nayak M, George A, Vidyasagar M, Mathew S, Nayak S, Nayak B . Quality of Life among Cancer Patients. Indian J Palliat Care. 2017; 23(4):445-450. PMC: 5661349. DOI: 10.4103/IJPC.IJPC_82_17. View

Cormie P, Zopf E, Zhang X, Schmitz K . The Impact of Exercise on Cancer Mortality, Recurrence, and Treatment-Related Adverse Effects. Epidemiol Rev. 2017; 39(1):71-92. DOI: 10.1093/epirev/mxx007. View

Marciniak C, Sliwa J, Heinemann A, Semik P . Functional outcomes of persons with brain tumors after inpatient rehabilitation. Arch Phys Med Rehabil. 2001; 82(4):457-63. DOI: 10.1053/apmr.2001.21862. View

Stout N, Baima J, Swisher A, Winters-Stone K, Welsh J . A Systematic Review of Exercise Systematic Reviews in the Cancer Literature (2005-2017). PM R. 2017; 9(9S2):S347-S384. PMC: 5679711. DOI: 10.1016/j.pmrj.2017.07.074. View

Mor V, Laliberte L, Morris J, Wiemann M . The Karnofsky Performance Status Scale. An examination of its reliability and validity in a research setting. Cancer. 1984; 53(9):2002-7. DOI: 10.1002/1097-0142(19840501)53:9<2002::aid-cncr2820530933>3.0.co;2-w. View

Guo Y, Ngo-Huang A, Fu J . Perspectives on Spinal Precautions in Patients Who Have Cancer and Spinal Metastasis. Phys Ther. 2020; 100(3):554-563. DOI: 10.1093/ptj/pzz178. View

Newcombe R . Two-sided confidence intervals for the single proportion: comparison of seven methods. Stat Med. 1998; 17(8):857-72. DOI: 10.1002/(sici)1097-0258(19980430)17:8<857::aid-sim777>3.0.co;2-e. View

Yoon H, Kim Y, Lim Y, Lee H, Choi K . Factors affecting quality of life of older adults with cancer in Korea. Geriatr Gerontol Int. 2014; 15(8):983-90. DOI: 10.1111/ggi.12378. View

10.

Hewitt M, Rowland J, Yancik R . Cancer survivors in the United States: age, health, and disability. J Gerontol A Biol Sci Med Sci. 2003; 58(1):82-91. DOI: 10.1093/gerona/58.1.m82. View

11.

Rizzo A . The Role of Exercise and Rehabilitation in the Cancer Care Plan. J Adv Pract Oncol. 2017; 7(3):339-342. PMC: 5679055. DOI: 10.6004/jadpro.2016.7.3.20. View

12.

Fitzmaurice C, Abate D, Abbasi N, Abbastabar H, Abd-Allah F, Abdel-Rahman O . Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncol. 2019; 5(12):1749-1768. PMC: 6777271. DOI: 10.1001/jamaoncol.2019.2996. View

13.

Knips L, Bergenthal N, Streckmann F, Monsef I, Elter T, Skoetz N . Aerobic physical exercise for adult patients with haematological malignancies. Cochrane Database Syst Rev. 2019; 1:CD009075. PMC: 6354325. DOI: 10.1002/14651858.CD009075.pub3. View

14.

Jette D, Stilphen M, Ranganathan V, Passek S, Frost F, Jette A . Interrater Reliability of AM-PAC "6-Clicks" Basic Mobility and Daily Activity Short Forms. Phys Ther. 2014; 95(5):758-66. DOI: 10.2522/ptj.20140174. View

15.

Campbell G, Hagan T, Gilbertson-White S, Houze M, Donovan H . Cancer and treatment-related symptoms are associated with mobility disability in women with ovarian cancer: A cross-sectional study. Gynecol Oncol. 2016; 143(3):578-583. PMC: 5116395. DOI: 10.1016/j.ygyno.2016.09.013. View

16.

Abdulwassi H, Amer I, Alhibshi A, Alnajjar A, Bahatheq A, Trabulsi N . Recurrence rates and long-term survival factors in young women with breast cancer. Saudi Med J. 2020; 41(4):393-399. PMC: 7841605. DOI: 10.15537/smj.2020.4.24987. View

17.

Leach C, Weaver K, Aziz N, Alfano C, Bellizzi K, Kent E . The complex health profile of long-term cancer survivors: prevalence and predictors of comorbid conditions. J Cancer Surviv. 2014; 9(2):239-51. DOI: 10.1007/s11764-014-0403-1. View

18.

Morris P . Moving our critically ill patients: mobility barriers and benefits. Crit Care Clin. 2007; 23(1):1-20. DOI: 10.1016/j.ccc.2006.11.003. View

19.

Jette D, Stilphen M, Ranganathan V, Passek S, Frost F, Jette A . Validity of the AM-PAC "6-Clicks" inpatient daily activity and basic mobility short forms. Phys Ther. 2013; 94(3):379-91. DOI: 10.2522/ptj.20130199. View

20.

Roh S, Yeom H, Lee M, Hwang I . Mobility of older palliative care patients with advanced cancer: a Korean study. Eur J Oncol Nurs. 2014; 18(6):613-8. DOI: 10.1016/j.ejon.2014.06.005. View