Emerging Roles and Mechanisms of LncRNA FOXD3-AS1 in Human Diseases

Overview

Journal Front Oncol

Specialty Oncology

Date 2022 Mar 14

PMID 35280790

Authors

Qinfan Yao

Xiuyuan Zhang

Dajin Chen

Affiliations

Soon will be listed here.

Abstract

Numerous long noncoding RNAs (lncRNAs) have been identified as powerful regulators of human diseases. The lncRNA FOXD3-AS1 is a novel lncRNA that was recently shown to exert imperative roles in the initialization and progression of several diseases. Emerging studies have shown aberrant expression of FOXD3-AS1 and close correlation with pathophysiological traits of numerous diseases, particularly cancers. More importantly, FOXD3-AS1 was also found to ubiquitously impact a range of biological functions. This study aims to summarize the expression, associated clinicopathological features, major functions and molecular mechanisms of FOXD3-AS1 in human diseases and to explore its possible clinical applications.

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