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Autism Spectrum Disorder in a Boy with Congenital Insensitivity to Pain with Anhidrosis: a Case Report

Overview
Journal BMC Pediatr
Publisher Biomed Central
Specialty Pediatrics
Date 2022 Mar 12
PMID 35277138
Authors
Mi Zhang
Xueqin Cao
Ningbo Li
Guangyou Duan
Xianwei Zhang
Affiliations
Soon will be listed here.
Abstract

Background: In this case report, we described the past history, clinical manifestations, genetic characteristics and cognitive evaluation of a boy with congenital insensitivity to pain with anhidrosis (CIPA) who developed autism spectrum disorder (ASD).

Case Presentation: The boy had an early onset of CIPA at the age of 48 months, and was later diagnosed with ASD at 5 years old. Developmental delays in communication, social skills and the presence of maladaptive behaviors were observed in the patient. Professional treatments significantly improved the developmental delays.

Conclusions: This case demonstrated that ASD may develop in children with CIPA, and pediatricians should be aware that if they suspect or identify a child with CIPA that they should also be screened for ASD using similar examination and diagnostic tools as shown in the present report. Moreover, therapeutic interventions for ASD was helpful for the remission of both diseases.

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