» Articles » PMID: 35268547

HIV-Associated Lymphomas: Progress and New Challenges

Overview
Journal J Clin Med
Specialty General Medicine
Date 2022 Mar 10
PMID 35268547
Authors
Affiliations
Soon will be listed here.
Abstract

The association of human immunodeficiency virus (HIV) and aggressive lymphomas was first reported in 1982. Before the development of effective HIV antiviral therapy, the incidence and the mortality of these lymphomas was high, with patients frequently succumbing to the disease. More lately, the combination of cART with chemoimmunotherapy significantly improved the survival outcome of the HIV-lymphomas. In this review, we discuss on describing the incidence of HIV-associated lymphomas, their clinical features, and the latest advances in the management of the various lymphoma subtypes.

Citing Articles

Synthesis and antitumor activity of dolutegravir derivatives bearing 1,2,3-triazole moieties.

Hou X, Mao L, Guo Y, Wang L, Peng L, Wang H BMC Chem. 2024; 18(1):97.

PMID: 38715128 PMC: 11077815. DOI: 10.1186/s13065-024-01205-3.


How can we establish animal models of HIV-associated lymphoma?.

Xiao Q, Zhai L, Zhang X, Liu Y, Li J, Xie X Animal Model Exp Med. 2024; 7(4):484-496.

PMID: 38567763 PMC: 11369037. DOI: 10.1002/ame2.12409.


Carcinogenic mechanisms of virus-associated lymphoma.

Zhang Y, Guo W, Zhan Z, Bai O Front Immunol. 2024; 15:1361009.

PMID: 38482011 PMC: 10932979. DOI: 10.3389/fimmu.2024.1361009.


The epidemiological patterns of non-Hodgkin lymphoma: global estimates of disease burden, risk factors, and temporal trends.

Chu Y, Liu Y, Fang X, Jiang Y, Ding M, Ge X Front Oncol. 2023; 13:1059914.

PMID: 37333805 PMC: 10272809. DOI: 10.3389/fonc.2023.1059914.


Clinical value of F-FDG PET/CT in the management of HIV-associated lymphoma.

Liu Q, Yang T, Chen X, Liu Y Front Oncol. 2023; 13:1117064.

PMID: 36776334 PMC: 9909962. DOI: 10.3389/fonc.2023.1117064.


References
1.
Scholler J, Brady T, Binder-Scholl G, Hwang W, Plesa G, Hege K . Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells. Sci Transl Med. 2012; 4(132):132ra53. PMC: 4368443. DOI: 10.1126/scitranslmed.3003761. View

2.
Murata T, Sugimoto A, Inagaki T, Yanagi Y, Watanabe T, Sato Y . Molecular Basis of Epstein-Barr Virus Latency Establishment and Lytic Reactivation. Viruses. 2021; 13(12). PMC: 8706188. DOI: 10.3390/v13122344. View

3.
Noy A . Optimizing treatment of HIV-associated lymphoma. Blood. 2019; 134(17):1385-1394. PMC: 7493463. DOI: 10.1182/blood-2018-01-791400. View

4.
Moulignier A, Lamirel C, Picard H, Lebrette M, Amiel C, Hamidi M . Long-term AIDS-related PCNSL outcomes with HD-MTX and combined antiretroviral therapy. Neurology. 2017; 89(8):796-804. DOI: 10.1212/WNL.0000000000004265. View

5.
Lurain K, Uldrick T, Ramaswami R, Polizzotto M, Goncalves P, Widell A . Treatment of HIV-associated primary CNS lymphoma with antiretroviral therapy, rituximab, and high-dose methotrexate. Blood. 2020; 136(19):2229-2232. PMC: 7645985. DOI: 10.1182/blood.2020006048. View