Phenotypes and Endotypes of Peach Allergy: What Is New?

Overview

Journal Nutrients

Date 2022 Mar 10

PMID 35267973

Authors

Simona Barni

Davide Caimmi

Fernanda Chiera

Pasquale Comberiati

Carla Mastrorilli

Umberto Pelosi

Francesco Paravati

Gian Luigi Marseglia

Stefania Arasi

Affiliations

Soon will be listed here.

Abstract

Peach allergy is emerging as a common type of fresh-fruit allergy in Europe, especially in the Mediterranean area. The clinical manifestations of peach allergy tend to have a peculiar geographical distribution and can range from mild oral symptoms to anaphylaxis, depending on the allergic sensitization profile. The peach allergen Pru p 7, also known as peamaclein, has recently been identified as a marker of peach allergy severity and as being responsible for peculiar clinical features in areas with high exposure to cypress pollen. This review addresses the latest findings on molecular allergens for the diagnosis of peach allergy, the clinical phenotypes and endotypes of peach allergy in adults and children, and management strategies, including immunotherapy, for peach allergy.

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