Blood Pressure and Vascular Cognitive Impairment
Overview
Affiliations
High blood pressure (BP) is detrimental to brain health. High BP contributes to cognitive impairment and dementia through pathways independent of clinical stroke. Emerging evidence shows that the deleterious effect of high BP on cognition occurs across the life span, increasing the risk for early-onset and late-life dementia. The term vascular cognitive impairment includes cognitive disorders associated with cerebrovascular disease, regardless of the pathogenesis. This focused report is a narrative review that aims to summarize the epidemiology of BP and vascular cognitive impairment, including differences by sex, race, and ethnicity, as well as the management and reversibility of BP and vascular cognitive impairment. It also discusses knowledge gaps and future directions.
Fekete M, Varga P, Ungvari Z, Fekete J, Buda A, Szappanos A Geroscience. 2025; .
PMID: 39797935 DOI: 10.1007/s11357-024-01488-3.
Wang H, Wu S, Pan D, Ning Y, Wang C, Guo J BMC Geriatr. 2024; 24(1):943.
PMID: 39543520 PMC: 11566281. DOI: 10.1186/s12877-024-05547-4.
Ouyang T, Zhang J, Tang Y, Yang Q BMC Geriatr. 2024; 24(1):870.
PMID: 39449111 PMC: 11515620. DOI: 10.1186/s12877-024-05349-8.
Blood Pressure and Cognitive Function in Older Adults.
Littig L, Sheth K, Brickman A, Mistry E, de Havenon A Clin Geriatr Med. 2024; 40(4):597-613.
PMID: 39349034 PMC: 11443062. DOI: 10.1016/j.cger.2024.04.003.
Association between blood pressure and dementia in older adults: a cross-sectional study from China.
Yi T, Su Z, Wang J, Gan J, Wu H, Shi Z Front Aging Neurosci. 2024; 16:1466089.
PMID: 39328244 PMC: 11425581. DOI: 10.3389/fnagi.2024.1466089.